| Title: |
Complications after surgery for benign prostatic enlargement: a population-based cohort study in Ontario, Canada |
| Authors: |
Rano Matta, Erind Dvorani, Christopher Wallis, Amanda Hird, Joseph LaBossiere, Girish Kulkarni, Ronald Kodama, Lesley Carr, Sidney B Radomski, Refik Saskin, Sender Herschorn, Robert K Nam |
| Source: |
BMJ Open, Vol 9, Iss 12 (2019) |
| Publisher Information: |
BMJ Publishing Group, 2019. |
| Publication Year: |
2019 |
| Collection: |
LCC:Medicine |
| Subject Terms: |
Medicine |
| More Details: |
Objectives To examine the complication rates after benign prostatic enlargement (BPE) surgery and the effects of age, comorbidity and preoperative medical therapy.Design A retrospective, population-based cohort study using linked administrative data.Setting Ontario, Canada.Participants 52 162 men≥66 years undergoing first BPE surgery between 1 January 2003 to 31 December 2014.Intervention Medical therapy preoperatively and surgery for BPE.Primary and secondary outcome measures The primary outcome was overall 30-day postoperative complication rates. Secondary outcomes included BPE-specific event rates (bleeding, infection, obstruction, trauma) and non-BPE specific event rates (cardiovascular, pulmonary, thromboembolic and renal). Multivariable analysis examined the association between preoperative medical therapy and postoperative complication rates.Results The 30-day overall complication rate after BPE surgery was 2828 events/10 000 procedures and increased annually over the study period. Receipt of preoperative α-blocker monotherapy (relative rate (RR) 1.05; 95% CI 1.00 to 1.09; p=0.033) and antithrombotic medications (RR 1.27; 95% CI 1.22 to 1.31; p |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2044-6055 |
| Relation: |
https://bmjopen.bmj.com/content/9/12/e032170.full; https://doaj.org/toc/2044-6055 |
| DOI: |
10.1136/bmjopen-2019-032170 |
| Access URL: |
https://doaj.org/article/c27ba983ca1c4062b1e180086969e6f1 |
| Accession Number: |
edsdoj.27ba983ca1c4062b1e180086969e6f1 |
| Database: |
Directory of Open Access Journals |
