| Title: |
Pediatric pan-central nervous system tumor analysis of immune-cell infiltration identifies correlates of antitumor immunity |
| Authors: |
Yura Grabovska, Alan Mackay, Patricia O’Hare, Stephen Crosier, Martina Finetti, Edward C. Schwalbe, Jessica C. Pickles, Amy R. Fairchild, Aimee Avery, Julia Cockle, Rebecca Hill, Janet Lindsey, Debbie Hicks, Mark Kristiansen, Jane Chalker, John Anderson, Darren Hargrave, Thomas S. Jacques, Karin Straathof, Simon Bailey, Chris Jones, Steven C. Clifford, Daniel Williamson |
| Source: |
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020) |
| Publisher Information: |
Nature Portfolio, 2020. |
| Publication Year: |
2020 |
| Collection: |
LCC:Science |
| Subject Terms: |
Science |
| More Details: |
Here, using methylCIBERSORT, the authors characterize the tumour-immune microenvironment of paediatric central nervous system (CNS) tumours and its association with tumour type and prognosis. These findings suggest that immuno-methylomic profiling may inform immunotherapy approaches in paediatric patients with CNS tumour. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2041-1723 |
| Relation: |
https://doaj.org/toc/2041-1723 |
| DOI: |
10.1038/s41467-020-18070-y |
| Access URL: |
https://doaj.org/article/ec15b2c4e08f447294d1c85b886169aa |
| Accession Number: |
edsdoj.15b2c4e08f447294d1c85b886169aa |
| Database: |
Directory of Open Access Journals |
