| Title: |
Distinct Profiles of DNA Repair Activity Define Favorable-risk Prostate Cancer Subtypes With Divergent Outcome |
| Authors: |
Swami, Nishwant, Nguyen, Tiffany, Ogobuiro, Ifeanyichukwu, Abramowitz, Matthew, Chipidza, Fallon, Davicioni, Elai, Meiyappan, Karthik, Pra, Alan Dal, Nguyen, Paul L., Pollack, Alan, Punnen, Sanoj, Mahal, Brandon A., Alshalalfa, Mohammed |
| Source: |
Clinical Genitourinary Cancer; 20220101, Issue: Preprints |
| Abstract: |
•This study first shows that high DNA repair activity is associated with high-risk prostate cancer.•Within low-risk prostate tumors, higher DNA repair activity is associated with poor outcome.•Within low-risk prostate patients who are candidates for active surveillance, high DNA repair activity defines a molecularly and clinically distinct subtype. |
| Database: |
Supplemental Index |
