| Title: |
Prognostic Criteria For Local Recurrence After Pancreaticoduodenectomy For Periampullary Carcinoma. |
| Authors: |
Khedr, Ali Hussein, Boushnak, Hussein Abdelaleem, Elgohary, Hatem, Baz, Yasser, Elshafey, Hossam E. |
| Source: |
Surgical Chronicles; Apr-Jun2023, Vol. 28 Issue 2, p112-116, 5p |
| Subject Terms: |
DISEASE risk factors, PANCREATICODUODENECTOMY, CANCER relapse, STATISTICAL significance, CANCER prognosis, PROGNOSIS, ADJUVANT treatment of cancer, SURGICAL margin, LYMPHATIC metastasis, POSTOPERATIVE period |
| Abstract: |
Background: Because periampullary carcinoma is uncommon, researches on it have not been active and the majority of the studies were small or retrospective. Prognostic variables for overall survival and recurrence in patients with periampullary carcinoma following surgery have been investigated in several studies. Aim of the work: was to determine the most important prognostic factors for recurrence following periampullary carcinoma curative resection. Methods: It was an observational study; it includes 20 patients who underwent Pancreaticoduodenectomy (PD) at Helwan university hospitals for periampullary cancer. Results: A statistical difference between the two groups concerning lymph node regional metastasis and vascular invasion, However, no statistically significant difference was found regarding degree of tumor differentiation, depth of tumor infiltration, perineural spread, resection margin status, posterior margin invasion and size of tumor. Conclusion: vascular invasion and lymph node involvement were the independent risk factors for initial recurrence of periampullary carcinoma after curative surgery. Therefore, Patients who meet these factors ought to be given aggressive adjuvant therapy and frequent postoperative monitoring. [ABSTRACT FROM AUTHOR] |
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| Database: |
Complementary Index |
