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Prognostic Criteria For Local Recurrence After Pancreaticoduodenectomy For Periampullary Carcinoma.

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Title: Prognostic Criteria For Local Recurrence After Pancreaticoduodenectomy For Periampullary Carcinoma.
Authors: Khedr, Ali Hussein, Boushnak, Hussein Abdelaleem, Elgohary, Hatem, Baz, Yasser, Elshafey, Hossam E.
Source: Surgical Chronicles; Apr-Jun2023, Vol. 28 Issue 2, p112-116, 5p
Subject Terms: DISEASE risk factors, PANCREATICODUODENECTOMY, CANCER relapse, STATISTICAL significance, CANCER prognosis, PROGNOSIS, ADJUVANT treatment of cancer, SURGICAL margin, LYMPHATIC metastasis, POSTOPERATIVE period
Abstract: Background: Because periampullary carcinoma is uncommon, researches on it have not been active and the majority of the studies were small or retrospective. Prognostic variables for overall survival and recurrence in patients with periampullary carcinoma following surgery have been investigated in several studies. Aim of the work: was to determine the most important prognostic factors for recurrence following periampullary carcinoma curative resection. Methods: It was an observational study; it includes 20 patients who underwent Pancreaticoduodenectomy (PD) at Helwan university hospitals for periampullary cancer. Results: A statistical difference between the two groups concerning lymph node regional metastasis and vascular invasion, However, no statistically significant difference was found regarding degree of tumor differentiation, depth of tumor infiltration, perineural spread, resection margin status, posterior margin invasion and size of tumor. Conclusion: vascular invasion and lymph node involvement were the independent risk factors for initial recurrence of periampullary carcinoma after curative surgery. Therefore, Patients who meet these factors ought to be given aggressive adjuvant therapy and frequent postoperative monitoring. [ABSTRACT FROM AUTHOR]
Copyright of Surgical Chronicles is the property of Surgical Society of Northern Greece and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Label: Title
  Group: Ti
  Data: Prognostic Criteria For Local Recurrence After Pancreaticoduodenectomy For Periampullary Carcinoma.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Khedr%2C+Ali+Hussein%22">Khedr, Ali Hussein</searchLink><br /><searchLink fieldCode="AR" term="%22Boushnak%2C+Hussein+Abdelaleem%22">Boushnak, Hussein Abdelaleem</searchLink><br /><searchLink fieldCode="AR" term="%22Elgohary%2C+Hatem%22">Elgohary, Hatem</searchLink><br /><searchLink fieldCode="AR" term="%22Baz%2C+Yasser%22">Baz, Yasser</searchLink><br /><searchLink fieldCode="AR" term="%22Elshafey%2C+Hossam+E%2E%22">Elshafey, Hossam E.</searchLink>
– Name: TitleSource
  Label: Source
  Group: Src
  Data: Surgical Chronicles; Apr-Jun2023, Vol. 28 Issue 2, p112-116, 5p
– Name: Subject
  Label: Subject Terms
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22DISEASE+risk+factors%22">DISEASE risk factors</searchLink><br /><searchLink fieldCode="DE" term="%22PANCREATICODUODENECTOMY%22">PANCREATICODUODENECTOMY</searchLink><br /><searchLink fieldCode="DE" term="%22CANCER+relapse%22">CANCER relapse</searchLink><br /><searchLink fieldCode="DE" term="%22STATISTICAL+significance%22">STATISTICAL significance</searchLink><br /><searchLink fieldCode="DE" term="%22CANCER+prognosis%22">CANCER prognosis</searchLink><br /><searchLink fieldCode="DE" term="%22PROGNOSIS%22">PROGNOSIS</searchLink><br /><searchLink fieldCode="DE" term="%22ADJUVANT+treatment+of+cancer%22">ADJUVANT treatment of cancer</searchLink><br /><searchLink fieldCode="DE" term="%22SURGICAL+margin%22">SURGICAL margin</searchLink><br /><searchLink fieldCode="DE" term="%22LYMPHATIC+metastasis%22">LYMPHATIC metastasis</searchLink><br /><searchLink fieldCode="DE" term="%22POSTOPERATIVE+period%22">POSTOPERATIVE period</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Background: Because periampullary carcinoma is uncommon, researches on it have not been active and the majority of the studies were small or retrospective. Prognostic variables for overall survival and recurrence in patients with periampullary carcinoma following surgery have been investigated in several studies. Aim of the work: was to determine the most important prognostic factors for recurrence following periampullary carcinoma curative resection. Methods: It was an observational study; it includes 20 patients who underwent Pancreaticoduodenectomy (PD) at Helwan university hospitals for periampullary cancer. Results: A statistical difference between the two groups concerning lymph node regional metastasis and vascular invasion, However, no statistically significant difference was found regarding degree of tumor differentiation, depth of tumor infiltration, perineural spread, resection margin status, posterior margin invasion and size of tumor. Conclusion: vascular invasion and lymph node involvement were the independent risk factors for initial recurrence of periampullary carcinoma after curative surgery. Therefore, Patients who meet these factors ought to be given aggressive adjuvant therapy and frequent postoperative monitoring. [ABSTRACT FROM AUTHOR]
– Name: Abstract
  Label:
  Group: Ab
  Data: <i>Copyright of Surgical Chronicles is the property of Surgical Society of Northern Greece and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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RecordInfo BibRecord:
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    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 5
        StartPage: 112
    Subjects:
      – SubjectFull: DISEASE risk factors
        Type: general
      – SubjectFull: PANCREATICODUODENECTOMY
        Type: general
      – SubjectFull: CANCER relapse
        Type: general
      – SubjectFull: STATISTICAL significance
        Type: general
      – SubjectFull: CANCER prognosis
        Type: general
      – SubjectFull: PROGNOSIS
        Type: general
      – SubjectFull: ADJUVANT treatment of cancer
        Type: general
      – SubjectFull: SURGICAL margin
        Type: general
      – SubjectFull: LYMPHATIC metastasis
        Type: general
      – SubjectFull: POSTOPERATIVE period
        Type: general
    Titles:
      – TitleFull: Prognostic Criteria For Local Recurrence After Pancreaticoduodenectomy For Periampullary Carcinoma.
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          Name:
            NameFull: Khedr, Ali Hussein
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            NameFull: Boushnak, Hussein Abdelaleem
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            NameFull: Elgohary, Hatem
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            NameFull: Baz, Yasser
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            NameFull: Elshafey, Hossam E.
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            – D: 01
              M: 04
              Text: Apr-Jun2023
              Type: published
              Y: 2023
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              Value: 28
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            – TitleFull: Surgical Chronicles
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