| Title: |
Determinants of Viral Resuppression or Persistent Virologic Failure After Initial Failure With Second-Line Antiretroviral Treatment Among Asian Children and Adolescents With HIV. |
| Authors: |
Teeraananchai, Sirinya, Kerr, Stephen J, Gandhi, Monica, Do, Viet Chau, Nguyen, Lam Van, Tran, Dan Ngoc Hanh, Kosalaraksa, Pope, Singtoroj, Thida, Thammajaruk, Narukjaporn, Jupimai, Thidarat, Sohn, Annette H |
| Source: |
Journal of the Pediatric Infectious Diseases Society; Jun2020, Vol. 9 Issue 2, p253-256, 4p |
| Subject Terms: |
DRUGS, HIV infections, GENETIC mutation, PATIENT compliance, RISK assessment, PROTEASE inhibitors, VIRAL load, ANTIRETROVIRAL agents, TREATMENT effectiveness, ADOLESCENCE, CHILDREN |
| Geographic Terms: |
ASIA |
| Abstract: |
Of 56 children with perinatally acquired human immunodeficiency virus (HIV) who had been prescribed second-line protease inhibitor–based antiretroviral therapy and had ≥1 previous episode of viral failure (HIV RNA, ≥1000 copies/mL), 46% had ≥1, 34% had ≥2, and 23% had ≥3 consecutive episodes of viral failure during the 2 years of follow-up. Two of these children experienced a major protease inhibitor mutation. [ABSTRACT FROM AUTHOR] |
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| Database: |
Complementary Index |
