Bibliographic Details
| Title: |
A cytosolic catalase is needed to extend adult lifespan in C. elegans daf-C and clk-1 mutants. |
| Authors: |
Taub, James, Lau, Joe F., Ma, Charles, Hahn, Jang Hee, Hoque, Rafaz, Rothblatt, Jonathan, Chalfie, Martin |
| Source: |
Nature. 5/13/1999, Vol. 399 Issue 6732, p162. 5p. 2 Color Photographs, 2 Black and White Photographs, 1 Chart, 11 Graphs. |
| Subjects: |
CAENORHABDITIS elegans, ANIMAL life spans, CATALASE, LARVAL physiology, PHYSIOLOGY, CYTOGENETICS |
| Abstract: |
Presents research which showed that a ctl-1 mutation in Caenorhabditis elegans reduces adult lifespan in otherwise wild-type animals. Features of the dauer larva stage for survival in periods of low food availability; Effects of mutations in daf-2, age-1 and clk-1; Encoding by ctl-1 and ctl-2; Need for the ctl-1 catalase in periods of starvation; Effects of the misexpression of ctl-1; Theory about the evolution of cytosolic catalase. |
| Database: |
MAS Ultra - School Edition |
