Bibliographic Details
| Title: |
Health-related quality of life associated with diabetic retinopathy in patients at a public primary care service in southern Brazil |
| Authors: |
Ben, Ângela Jornada, Souza, Camila Furtado de, Locatelli, Franciele, Rosses, Ana Paula Oliveira, Szortika, Adriana, Araujo, Aline Lutz de, Carvalho, Gabriela de, Lavinsky, Daniel, Neyeloff, Jeruza Lavanholi, Neumann, Cristina Rolim |
| Source: |
Archives of Endocrinology and Metabolism. October 2020 64(5) |
| Publisher Information: |
Sociedade Brasileira de Endocrinologia e Metabologia, 2020. |
| Publication Year: |
2020 |
| Subject Terms: |
EQ-5D, health-related quality of life, utility values, diabetic retinopathy |
| More Details: |
Objective This study aimed to establish the utility values of different health states associated with diabetic retinopathy in a Brazilian sample to provide input to model-based economic evaluations. Subjects and methods This cross-sectional study was performed in a sample of patients with type 2 diabetes mellitus (T2D) who underwent teleophthalmology screening at a primary care service from 2014 to 2016. Five diabetic retinopathy health states were defined: absent, non-sight-threatening, sight-threatening, and bilateral blindness. Utility values were estimated using the Brazilian EuroQol five dimensions (EQ-5D) tariffs. Descriptive statistics were calculated. Analysis of covariance was performed to adjust the utility values for potential confounders. Results The study included 206 patients. The mean (± standard deviation [SD]) utility value was 0.765 ± 0.19 (95% confidence interval [CI], 0.740–0.790). The adjusted mean utility value was 0.748 (95% CI, 0.698–0.798) in patients without diabetic retinopathy, 0.752 (95% CI, 0.679–0.825) in those with non-sight-threatening state, 0.628 (95% CI, 0.521–0.736) in those with sight-threatening state, and 0.355 (95% CI, 0.105–0.606) in those with bilateral blindness. A significant utility decrement was found between patients without diabetic retinopathy and those with a sight-threatening health state (0.748 vs. 0.628, respectively, p = 0.04). Conclusions The findings suggest that a later diabetic retinopathy health state is associated with a decrement in utility value compared with the absence of retinopathy in patients with T2D. The results may be useful as preliminary input to model-based economic evaluations. Further research is needed to investigate the impact of diabetic retinopathy on health-related quality of life in a sample more representative of the Brazilian population. |
| Document Type: |
article |
| File Description: |
text/html |
| Language: |
English |
| ISSN: |
2359-3997 |
| DOI: |
10.20945/2359-3997000000223 |
| Access URL: |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2359-39972020000500575 |
| Rights: |
info:eu-repo/semantics/openAccess |
| Accession Number: |
edssci.S2359.39972020000500575 |
| Database: |
SciELO |
