Bibliographic Details
| Title: |
Retrospective analysis on efficacy of convalescent plasma in acute respiratory distress syndrome due to COVID-19 |
| Authors: |
Eren, Esma, Ulu-Kılıç, Ayşegül, Korkmaz, Serdal, Yıldız, Merve, Yüksel, Recep Civan, Kılınç-Toker, Ayşin, Arman-Fırat, Emine, Bestepe-Dursun, Zehra, Çelik, Ilhami |
| Source: |
Sao Paulo Medical Journal. February 2022 140(1) |
| Publisher Information: |
Associação Paulista de Medicina - APM, 2022. |
| Publication Year: |
2022 |
| Subject Terms: |
COVID-19, Respiratory distress syndrome, COVID-19 serotherapy [supplementary concept], Coronavirus disease 2019, Convalescent plasma, Acute respiratory distress syndrome. |
| More Details: |
BACKGROUND: Coronavirus disease 2019 (COVID-19) is an ongoing global health threat. However, currently, no standard therapy has been approved for the disease. OBJECTIVES: To evaluate the clinical effectiveness of convalescent plasma (CP) in patients with acute respiratory distress syndrome (ARDS) due to COVID-19. DESIGN AND SETTING: Retrospective study conducted at Kayseri City Education and Research Hospital, Kayseri, Turkey. METHODS: The case group consisted of adult patients (> 18 years) with ARDS due to COVID-19 who received CP in combination with antiviral and supportive treatment. These patients were compared with others who only received antiviral and supportive treatment. RESULTS: During the study period, a total of 30 patients with ARDS due to COVID-19 were included. Eleven patients (36%) received CP in combination with antiviral and supportive treatment, whereas nineteen patients (64%) in the control group only received antiviral and supportive treatment. On admission, the median age, demographic and clinical data and initial laboratory test results were similar between the groups (P > 0.05). On the 14th day of treatment, the laboratory values remained similar between the groups (P > 0.05). The mortality rates were not significantly different between the groups. CONCLUSION: CP treatment did not affect mortality or lead to clinical improvement for COVID-19 patients with ARDS. |
| Document Type: |
article |
| File Description: |
text/html |
| Language: |
English |
| ISSN: |
1516-3180 |
| DOI: |
10.1590/1516-3180.2021.0200.r1.03052021 |
| Access URL: |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802022000100012 |
| Rights: |
info:eu-repo/semantics/openAccess |
| Accession Number: |
edssci.S1516.31802022000100012 |
| Database: |
SciELO |
