Bibliographic Details
| Title: |
Vitamin D and bone health in adults: a systematic review and meta-analysis |
| Authors: |
Segheto, Kátia Josiany, Pereira, Marcos, Silva, Danielle Cristina Guimarães da, Carvalho, Cristiane Junqueira de, Massardi, Felipe Ribeiro, Kakehasi, Adriana Maria, Juvanhol, Leidjaira Lopes, Longo, Giana Zarbato |
| Source: |
Ciência & Saúde Coletiva. August 2021 26(8) |
| Publisher Information: |
ABRASCO - Associação Brasileira de Saúde Coletiva, 2021. |
| Publication Year: |
2021 |
| Subject Terms: |
Mineral density, Vitamin D, Adults |
| More Details: |
Low bone health is associated with vitamin D deficiency in older individuals; however, this association is not well established in adults. The aim of the study was to analyze the association between serum concentrations of 25-hydroxyvitamin D and bone health in adults by systematic review and meta-analysis. The search was carried out in the LILACS, PubMed, Scopus, Web of Science, ScienceDirect databases from March 2017 to October 2018 with adult individuals (20-59 years). Bone health was evaluation performed through dual X-ray absorptiometry and serum concentrations of 25(OH)D. The random effect model was used to analyze data from bone mineral content and bone mineral. Random effects models were used and the sources of heterogeneity were explored by means of meta-regression. Thirty-five articles were selected. There was positive correlation between vitamin D and bone health in most of the evaluated sites. Correlation was observed in the analysis of subgroups for lumbar spine among men. When stratified, the studies presented high heterogeneity, which was explained by the sample size, mean serum vitamin D levels and risk of bias. Vitamin D is positively correlated to bone health in adult individuals. |
| Document Type: |
article |
| File Description: |
text/html |
| Language: |
English |
| ISSN: |
1413-8123 |
| DOI: |
10.1590/1413-81232021268.15012020 |
| Access URL: |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-81232021000803221 |
| Rights: |
info:eu-repo/semantics/openAccess |
| Accession Number: |
edssci.S1413.81232021000803221 |
| Database: |
SciELO |
