Bibliographic Details
| Title: |
'Sweet Chemistry': a Green Way for Obtaining Selenium Nanoparticles Active against Cancer Cells |
| Authors: |
Vieira, Adriana P., Stein, Erika M., Andreguetti, Daniel X., Cebrián-Torrejón, Gerardo, Doménech-Carbó, Antonio, Colepicolo, Pio, Ferreira, Ana Maria D. C. |
| Source: |
Journal of the Brazilian Chemical Society. October 2017 28(10) |
| Publisher Information: |
Sociedade Brasileira de Química, 2017. |
| Publication Year: |
2017 |
| Subject Terms: |
selenium nanoparticles, D-fructose, cancer cells, green chemistry, cytotoxicity |
| More Details: |
We present an environment friendly synthesis of selenium nanoparticles and the study of their cytotoxic activity against uterine sarcoma cancer and fibroblasts cells. Amorphous selenium (a-SeNPs) and trigonal selenium (t-SeNPs) were synthesized using D-fructose as the reducing agent and characterized by high-resolution transmission electron microscopy (HRTEM), energy-dispersive X-ray spectroscopy (EDX), powder X-ray diffraction analysis (XRD), inductively coupled plasma optical emission spectrometry (ICP OES), dynamic light scattering (DLS) to obtain zeta potential values and cyclic voltammetry (CV). Particularly, a-SeNPs presented high toxicity toward the resistant cancer cell line MES-SA/Dx5 and its parental MES-SA line. However, they are not toxic against P4 fibroblast cells in comparative studies. |
| Document Type: |
article |
| File Description: |
text/html |
| Language: |
English |
| ISSN: |
0103-5053 |
| DOI: |
10.21577/0103-5053.20170025 |
| Access URL: |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532017001002021 |
| Rights: |
info:eu-repo/semantics/openAccess |
| Accession Number: |
edssci.S0103.50532017001002021 |
| Database: |
SciELO |
