| Title: |
HIV-1 seroprevalence in the general population of Salvador, Bahia State, Northeast Brazil |
| Authors: |
Dourado, Inês, Milroy, Craig A., Mello, Marco Antônio Gomes, Ferraro, Geraldo Argolo, Castro-Lima Filho, Humberto, Guimarães, Monick Lindenmeyer, Morgado, Mariza Gonçalves, Teixeira, Maria Gloria, Barreto, Maurício L., Galvão-Castro, Bernardo |
| Source: |
Cadernos de Saúde Pública. January 2007 23(1) |
| Publisher Information: |
Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz, 2007. |
| Publication Year: |
2007 |
| Subject Terms: |
HIV-1, HIV Seroprevalence, Cross-sectional Studies |
| More Details: |
To estimate HIV-1 seroprevalence in the general population of Salvador, Bahia, Brazil, we conducted a cross-sectional survey of 3,437 residents from 1998 to 2000. Subjects were drawn from 30 sentinel areas representing a wide range of living conditions. Plasma samples were screened for HIV-1 antibodies by ELISA and confirmed by immunofluorescent assay. Subtype determination by HMA was performed after proviral DNA amplification. Phylogenetic analysis using parsimony was performed with the neighbor-joining method. Overall HIV-1 seroprevalence was 0.55% (19/3,446): 0.8% for men and 0.36% for women. Seroprevalence was higher in the 31-45-year age group (1%) and among persons with family income less than twice the minimum wage (0.78%) as compared to 0.33% for the higher income group. Syphilis was detected in 37% of HIV seropositive individuals. Phylogenetic inferences identified 10 samples as subtype B in the env region and 2 samples with Benv/Fgag/Fpol and Fenv/Bgag. Age > 30 years, male gender, and income < 2 times the minimum wage were identified as risk factors for HIV-1 infection. Extrapolating the proportion of seropositive individuals to Salvador, the number of HIV-1 infected individuals was estimated at 13,750. |
| Document Type: |
article |
| File Description: |
text/html |
| Language: |
English |
| ISSN: |
0102-311X |
| DOI: |
10.1590/S0102-311X2007000100004 |
| Access URL: |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-311X2007000100004 |
| Rights: |
info:eu-repo/semantics/openAccess |
| Accession Number: |
edssci.S0102.311X2007000100004 |
| Database: |
SciELO |
