Bibliographic Details
| Title: |
Magnetic resonance imaging at 3.0-T in postmenopausal osteoporosis: a prospective study and review of the literature |
| Authors: |
Trentadue, Mirko, Sozzi, Carlo, Idolazzi, Luca, Lazzarini, Gianluigi, Murano, Riccardo Sante, Gatti, Davide, Rossini, Maurizio, Piovan, Enrico |
| Source: |
Radiologia Brasileira. January 2022 |
| Publisher Information: |
Publicação do Colégio Brasileiro de Radiologia e Diagnóstico por Imagem, 2022. |
| Publication Year: |
2022 |
| Subject Terms: |
Osteoporosis, Postmenopause, Vertebral body/pathology, Multiparametric magnetic resonance imaging/methods, Bone marrow/pathology |
| More Details: |
Objective: To promote advanced research using magnetic resonance imaging (MRI) in the diagnosis of and screening for osteoporosis by looking for correlations among the T-scores measured by dual-energy X-ray absorptiometry (DEXA), the apparent diffusion coefficient (ADC) values on diffusion-weighted imaging (DWI), and the T1-weighted signal intensity values. Materials and Methods: This was a prospective study of postmenopausal women with no contraindications to MRI and no history of cancer who underwent DEXA within 30 days before or after the MRI examination. A 3.0-T scanner was used in order to acquire sagittal sequences targeting the lumbar spine. Results: Thirteen women underwent DEXA and MRI. In two cases, the MRI was discontinued early. Therefore, the final sample comprised 11 patients. The ADC values and T1-weighted signal intensity were found to be higher in patients with osteoporosis. However, among the patients > 60 years of age with osteoporosis, ADC values were lower and T1-weighted signal intensity was even higher. Conclusion: It is unlikely that MRI will soon replace DEXA for the diagnostic workup of osteoporosis. Although DWI and ADC mapping are useful for understanding the pathophysiology of osteoporosis, we believe that T1-weighted sequences are more sensitive than is DWI as a means of performing a qualitative analysis of vertebral alterations. |
| Document Type: |
article |
| File Description: |
text/html |
| Language: |
English |
| ISSN: |
0100-3984 |
| DOI: |
10.1590/0100-3984.2021.0124 |
| Access URL: |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-39842022005001216 |
| Rights: |
info:eu-repo/semantics/openAccess |
| Accession Number: |
edssci.S0100.39842022005001216 |
| Database: |
SciELO |
