Bibliographic Details
| Title: |
Molecular epidemiology of human immunodeficiency virus-1 in the state of Ceará, Northeast, Brazil |
| Authors: |
Gadelha, Sandra Rocha, Shindo, Nice, Cruz, José Napoleão Monte, Morgado, Mariza Gonçalves, Galvão-Castro, Bernardo |
| Source: |
Memórias do Instituto Oswaldo Cruz. June 2003 98(4) |
| Publisher Information: |
Instituto Oswaldo Cruz, Ministério da Saúde, 2003. |
| Publication Year: |
2003 |
| Subject Terms: |
human immunodeficiency virus, molecular epidemiology, Ceará, Brazil |
| More Details: |
We analyzed, by env and gag heteroduplex mobility assay, 149 human immunodeficiency virus (HIV-1) positive samples collected in Ceará during the year 2000. The prevalence of subtype B was 81.2% and the prevalence of subtype F and B/F recombinants were both 2.7%. Eight (5.4%) and 12 (8%) out of 149 samples showed indeterminate results in the env and gag analysis respectively. By FokI restriction fragment length polymorphism, 34% of the subtype B samples were identified as the typical Brazilian subtype B.In the present study, we identified HIV-1 subtype F and B/F in Ceará for the first time. Our results contribute to the understanding of HIV in Brazil, and may prove useful for the development of vaccine candidates. |
| Document Type: |
article |
| File Description: |
text/html |
| Language: |
English |
| ISSN: |
0074-0276 |
| DOI: |
10.1590/S0074-02762003000400005 |
| Access URL: |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762003000400005 |
| Rights: |
info:eu-repo/semantics/openAccess |
| Accession Number: |
edssci.S0074.02762003000400005 |
| Database: |
SciELO |
