Bibliographic Details
| Title: |
Influence of a subinhibitory concentration of vancomycin on the in vitro expression of virulence-related genes in the vancomycin-resistant Enterococcus faecalis |
| Authors: |
Moura, Tiane Martin de, Campos, Fabrício Souza, Caierão, Juliana, Franco, Ana Claudia, Roehe, Paulo Michel, d'Azevedo, Pedro Alves, Frazzon, Jeverson, Frazzon, Ana Paula Guedes |
| Source: |
Revista da Sociedade Brasileira de Medicina Tropical. October 2015 48(5) |
| Publisher Information: |
Sociedade Brasileira de Medicina Tropical - SBMT, 2015. |
| Publication Year: |
2015 |
| Subject Terms: |
VRE, Biofilm, Expression |
| More Details: |
NTRODUCTION:Exposure to subinhibitory concentrations (SICs) of antimicrobials may alter the bacterial transcriptome.METHODS: Here, we evaluated the expression of nine virulence-related genes in vancomycin-resistant enterococci (VRE) urinary tract infection isolates grown at SICs of vancomycin.RESULTS:A Subinhibitory concentrations of vancomycin interferes with gene modulation, but does not affect the phenotype of a VRE strain in vitro .CONCLUSIONS:Subinhibitory concentrations of vancomycin may regulate the expression of virulence factors in vivo or contribute to the selection of vancomycin-resistant strains. |
| Document Type: |
other |
| File Description: |
text/html |
| Language: |
English |
| ISSN: |
0037-8682 |
| DOI: |
10.1590/0037-8682-0017-2015 |
| Access URL: |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822015000500617 |
| Rights: |
info:eu-repo/semantics/openAccess |
| Accession Number: |
edssci.S0037.86822015000500617 |
| Database: |
SciELO |
