Bibliographic Details
| Title: |
A Case-Control study of the prevalence of neurological diseases in inflammatory bowel disease (IBD) |
| Authors: |
Gondim, Francisco de Assis Aquino, Oliveira, Gisele Ramos de, Teles, Benedito Cadorno V., Souza, Marcellus H.L.P., Braga, Lucia L.B.C., Messias, Erick L. |
| Source: |
Arquivos de Neuro-Psiquiatria. February 2015 73(2) |
| Publisher Information: |
Academia Brasileira de Neurologia - ABNEURO, 2015. |
| Publication Year: |
2015 |
| Subject Terms: |
Chron's disease, inflammatory bowel disease, peripheral neuropathy, small fiber neuropathy, ulcerative colitis |
| More Details: |
Neurological diseases are common in inflammatory bowel disease (IBD) patients, but their exact prevalence is unknown. Method We prospectively evaluated the presence of neurological disorders in 121 patients with IBD [51 with Crohn's disease (CD) and 70 with ulcerative colitis (UC)] and 50 controls (gastritis and dyspepsia) over 3 years. Results Our standard neurological evaluation (that included electrodiagnostic testing) revealed that CD patients were 7.4 times more likely to develop large-fiber neuropathy than controls (p = 0.045), 7.1 times more likely to develop any type of neuromuscular condition (p = 0.001) and 5.1 times more likely to develop autonomic complaints (p = 0.027). UC patients were 5 times more likely to develop large-fiber neuropathy (p = 0.027) and 3.1 times more likely to develop any type of neuromuscular condition (p = 0.015). Conclusion In summary, this is the first study to prospectively establish that both CD and UC patients are more prone to neuromuscular diseases than patients with gastritis and dyspepsia. |
| Document Type: |
article |
| File Description: |
text/html |
| Language: |
English |
| ISSN: |
0004-282X |
| DOI: |
10.1590/0004-282X20140223 |
| Access URL: |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2015000200119 |
| Rights: |
info:eu-repo/semantics/openAccess |
| Accession Number: |
edssci.S0004.282X2015000200119 |
| Database: |
SciELO |
