Motion visualisation in angiographic images
| Title: | Motion visualisation in angiographic images |
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| Patent Number: | 9,025,840 |
| Publication Date: | May 05, 2015 |
| Appl. No: | 13/582124 |
| Application Filed: | March 04, 2011 |
| Abstract: | A method and an apparatus for motion visualization of a moving object in angiographic images are described. In a preferred embodiment of the method, first a mask image of the object of interest is acquired and a sequence of angiographic images of the object in different phases of motion of the object is acquired. Then, a first angiographic subtraction image and at least a second angiographic subtraction image are generated by subtracting the angiographic images from the mask image. Subsequently, a twice subtracted image is generated by subtracting the first angiographic subtraction image from the second angiographic subtraction image. In this way a double subtraction, i.e. a twice subtracted angiography is performed, to facilitate the assessment of the motion. |
| Inventors: | Waechter-Stehle, Irina (Hamburg, DE); Groth, Alexandra (Hamburg, DE); Hermans, Ronaldus Petrus Johannes (Den Bosch, NL); Bertram, Matthias (Aachen, DE) |
| Assignees: | Koninklijke Philips N.V. (Eindhoven, NL) |
| Claim: | 1. A method for motion visualization of a moving object in angiographic images, the method comprising: acquiring a sequence of angiographic images of the object in different phases of motion of the object and a mask image of the object; generating a first angiographic subtraction image and at least a second angiographic subtraction image by subtracting the angiographic images from the mask image; and generating a twice subtracted image by subtracting the first angiographic subtraction image from the second angiographic subtraction image. |
| Claim: | 2. The method according to claim 1 , further comprising averaging angiographic subtraction images representing the object in the same phase of motion. |
| Claim: | 3. The method according to claim 1 , further comprising the step of selecting the first angiographic subtraction image such that the phase of motion represented in the first angiographic subtraction image is an extreme phase of motion. |
| Claim: | 4. The method according to claim 1 , wherein the first angiographic subtraction image and the second angiographic subtraction image represent different phases of motion of the object. |
| Claim: | 5. The method according to claim 1 , wherein the phase of motion represents a phase of a periodical motion of the object. |
| Claim: | 6. The method according to claim 1 , further comprising determining the phase of motion in at least two angiographic subtraction images. |
| Claim: | 7. The method according to claim 6 , further comprising acquiring a motion signal representative of the phase of motion of the object; wherein the determination of the phase of motion in the angiographic subtraction images is based on the motion signal. |
| Claim: | 8. The method according to claim 6 , wherein determination of the phase of motion in the angiographic subtraction images is based on an analysis of the subtraction angiographic images. |
| Claim: | 9. The method according to claim 1 , further comprising selecting angiographic subtraction images in which contrast agent is present in the object. |
| Claim: | 10. The method according to claim 1 , wherein the steps of the method are executed automatically. |
| Claim: | 11. The method according to claim 1 , further comprising determining a spatial correspondence between at least two of the angiographic images. |
| Claim: | 12. The method according to claim 1 , wherein the moving object is one of an aneurism, a vessel structure, a vessel malformation and a heart; wherein the phase of motion represent the phase of a heart cycle and/or a phase of a respiration cycle. |
| Claim: | 13. An apparatus, for motion visualization of a moving object in angiographic images, the apparatus comprising: a first subtractor for generating a first angiographic subtraction image and at least a second angiographic subtraction image by subtracting angiographic images from a mask image; and a second subtractor for generating a twice subtracted image by subtracting the first angiographic subtraction image from the second angiographic subtraction image. |
| Claim: | 14. The apparatus of claim 13 , configured for averaging angiographic subtraction images representing the object in the same phase of motion. |
| Claim: | 15. The apparatus of claim 13 , the first and second subtractors being configured for performing their respective generating, from the corresponding images, automatically, without need for user interaction. |
| Claim: | 16. The apparatus of claim 13 , said angiographic images being of the object in different phases of motion of the object, said apparatus being configured for selecting the first angiographic subtraction image such that the phase of motion represented in the first angiographic subtraction image is an extreme phase of motion. |
| Claim: | 17. The apparatus of claim 13 , the first angiographic subtraction image and the second angiographic subtraction image representing different phases of motion of the object. |
| Claim: | 18. The apparatus of claim 13 , said angiographic images being of the object in different phases of motion of the object, the phase of motion representing a phase of a cyclical motion of the object. |
| Claim: | 19. The apparatus of claim 13 , configured for determining, from among said first angiographic subtraction image and at least a second angiographic subtraction image, the phase of motion in at least two angiographic subtraction images. |
| Claim: | 20. A computer readable medium embodying a computer program for motion visualization of a moving object in angiographic images, said program having instructions executable by a processor for performing a plurality of acts, among said plurality there being the acts of: acquiring a sequence of angiographic images of the object in different phases of motion of the object and a mask image of the object; generating a first angiographic subtraction image and at least a second angiographic subtraction image by subtracting the angiographic images from the mask image; and generating a twice subtracted image by subtracting the first angiographic subtraction image from the second angiographic subtraction image. |
| Current U.S. Class: | 382/130 |
| Patent References Cited: | 7545967 June 2009 Prince et al. 8428220 April 2013 Buijns et al. 8498463 July 2013 Florent et al. 2007/0104317 May 2007 Ohishi 2009/0067568 March 2009 Hall et al. 10031745 February 1998 2006271484 October 2006 2009297077 December 2009 WO2008053401 May 2008 |
| Other References: | E. Oubel et al, “Analysis of Interacranial Aneurysm Wall Motion and Its Effects on Hemodynamic Patterns”, Proceedings of the SPIE—the International Society for Optical Engineering SPIE—the International Society for Optical Engineering USA, vol. 6511, 2007. cited by applicant M. Sonka et al, “Image Processing, Analysis, and Machine Vision, Second Edition”, Pacific Grove, Calif, Jan. 1, 1999, pp. 679-685. cited by applicant Schad, “Nontraumatic Assessment of Left Ventricular Wall Motion and Regional Stroke Volume After Myocardial Infarction”, Journal of Nuclear Medicine, Vol. 18, No. 4, 1977, pp. 333-341. cited by applicant Anxionnat et al, “Intracranial Aneurysms: Clinical Value of 3D Digital Subtraction Angiography in the Therapeutic Decision and Endovascular Treatment”, Radiology, Vol. 218, 2001, pp. 799-808. cited by applicant Sonka et al, “Chapter 15 Motion Analysis, 15.1 Differential Motion Analysis Methods”, Image Processing Analysis and Machine Vision, Jan. 1, 1999, pp. 679-685. cited by applicant Cui, “Research on Moving Object Detection and Dtracking in Image Sequence”, China Master'S Theses, No. 7, 2009, 79 Page Document. cited by applicant Oubel et al, “Analysis of Intracranial Aneurysm Wall Motion and Its Effects on Hemodynamic Patterns”, Proceedings of the SPIE, Vol. 6511, 2007, pp. 1-8. cited by applicant |
| Primary Examiner: | Tabatabai, Abolfazl |
| Accession Number: | edspgr.09025840 |
| Database: | USPTO Patent Grants |
| Language: | English |
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