Allosteric inhibition of tRNA synthetase Gln4 by N-pyrimidinyl-β-thiophenylacrylamides exerts highly selective antifungal activity
Title: | Allosteric inhibition of tRNA synthetase Gln4 by N-pyrimidinyl-β-thiophenylacrylamides exerts highly selective antifungal activity |
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Authors: | Puumala, Emily, Sychantha, David, Lach, Elizabeth, Reeves, Shawn, Nabeela, Sunna, Fogal, Meea, Nigam, AkshatKumar, Johnson, Jarrod W., Aspuru-Guzik, Alán, Shapiro, Rebecca S., Uppuluri, Priya, Kalyaanamoorthy, Subha, Magolan, Jakob, Whitesell, Luke, Robbins, Nicole, Wright, Gerard D., Cowen, Leah E. |
Source: | In Cell Chemical Biology 18 April 2024 31(4):760-775 |
Database: | ScienceDirect |
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