Allosteric inhibition of tRNA synthetase Gln4 by N-pyrimidinyl-β-thiophenylacrylamides exerts highly selective antifungal activity

Bibliographic Details
Title: Allosteric inhibition of tRNA synthetase Gln4 by N-pyrimidinyl-β-thiophenylacrylamides exerts highly selective antifungal activity
Authors: Puumala, Emily, Sychantha, David, Lach, Elizabeth, Reeves, Shawn, Nabeela, Sunna, Fogal, Meea, Nigam, AkshatKumar, Johnson, Jarrod W., Aspuru-Guzik, Alán, Shapiro, Rebecca S., Uppuluri, Priya, Kalyaanamoorthy, Subha, Magolan, Jakob, Whitesell, Luke, Robbins, Nicole, Wright, Gerard D., Cowen, Leah E.
Source: In Cell Chemical Biology 18 April 2024 31(4):760-775
Database: ScienceDirect
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ISSN:24519456
DOI:10.1016/j.chembiol.2024.01.010
Published in:Cell Chemical Biology
Language:English