Design and evaluation of achiral, non-atropisomeric 4-(aminomethyl)phthalazin-1(2H)-one derivatives as novel PRMT5/MTA inhibitors
| Title: | Design and evaluation of achiral, non-atropisomeric 4-(aminomethyl)phthalazin-1(2H)-one derivatives as novel PRMT5/MTA inhibitors |
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| Authors: | Smith, Christopher R., Aranda, Ruth, Christensen, James G., Engstrom, Lars D., Gunn, Robin J., Ivetac, Anthony, Ketcham, John M., Kuehler, Jon, David Lawson, J., Marx, Matthew A., Olson, Peter, Thomas, Nicole C., Wang, Xiaolun, Waters, Laura M., Kulyk, Svitlana |
| Source: | In Bioorganic & Medicinal Chemistry 1 October 2022 71 |
| Database: | ScienceDirect |
| ISSN: | 09680896 |
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| DOI: | 10.1016/j.bmc.2022.116947 |
| Published in: | Bioorganic & Medicinal Chemistry |
| Language: | English |