Structure-guided optimization of 4,6-substituted-1,3,5-triazin-2(1H)-ones as catalytic inhibitors of human DNA topoisomerase IIα
| Title: | Structure-guided optimization of 4,6-substituted-1,3,5-triazin-2(1H)-ones as catalytic inhibitors of human DNA topoisomerase IIα |
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| Authors: | Bergant, Kaja, Janežič, Matej, Valjavec, Katja, Sosič, Izidor, Pajk, Stane, Štampar, Martina, Žegura, Bojana, Gobec, Stanislav, Filipič, Metka, Perdih, Andrej |
| Source: | In European Journal of Medicinal Chemistry 1 August 2019 175:330-348 |
| Database: | ScienceDirect |
| ISSN: | 02235234 |
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| DOI: | 10.1016/j.ejmech.2019.04.055 |
| Published in: | European Journal of Medicinal Chemistry |
| Language: | English |