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The novel, catalytic mTORC1/2 inhibitor PQR620 and the PI3K/mTORC1/2 inhibitor PQR530 effectively cross the blood-brain barrier and increase seizure threshold in a mouse model of chronic epilepsy

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Title: The novel, catalytic mTORC1/2 inhibitor PQR620 and the PI3K/mTORC1/2 inhibitor PQR530 effectively cross the blood-brain barrier and increase seizure threshold in a mouse model of chronic epilepsy
Authors: Brandt, Claudia, Hillmann, Petra, Noack, Andreas, Römermann, Kerstin, Öhler, Leon A., Rageot, Denise, Beaufils, Florent, Melone, Anna, Sele, Alexander M., Wymann, Matthias P., Fabbro, Doriano, Löscher, Wolfgang
Source: In Neuropharmacology 15 September 2018 140:107-120
Database: ScienceDirect
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ISSN:00283908
DOI:10.1016/j.neuropharm.2018.08.002
Published in:Neuropharmacology
Language:English