Inactivating PSMB5 Mutations and P-Glycoprotein (Multidrug Resistance-Associated Protein/ATP-Binding Cassette B1) Mediate Resistance to Proteasome Inhibitors: Ex Vivo Efficacy of (Immuno)Proteasome Inhibitors in Mononuclear Blood Cells from Patients with Rheumatoid Arthritis

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Title: Inactivating PSMB5 Mutations and P-Glycoprotein (Multidrug Resistance-Associated Protein/ATP-Binding Cassette B1) Mediate Resistance to Proteasome Inhibitors: Ex Vivo Efficacy of (Immuno)Proteasome Inhibitors in Mononuclear Blood Cells from Patients with Rheumatoid Arthritis
Authors: Verbrugge, Sue Ellen, Assaraf, Yehuda G., Dijkmans, Ben A.C., Scheffer, George L., Al, Marjon, den Uyl, Debby, Oerlemans, Ruud, Chan, Elena T., Kirk, Christopher J., Peters, Godefridus J., van der Heijden, Joost W., de Gruijl, Tanja D., Scheper, Rik J., Jansen, Gerrit *
Source: In The Journal of Pharmacology and Experimental Therapeutics April 2012 341(1):174-182
Database: ScienceDirect
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ISSN:00223565
DOI:10.1124/jpet.111.187542
Published in:The Journal of Pharmacology and Experimental Therapeutics
Language:English