Bibliographic Details
| Title: |
Insulin resistance accelerated the clearance of resveratrol: A note of caution |
| Authors: |
Zhixia Qiu, Qiuyan Liu, Jiaojiao Yu, Yu Dai, Xiaonan Li, Fang Huang, Ning Li |
| Source: |
Journal of Functional Foods, Vol 58, Iss , Pp 311-323 (2019) |
| Publisher Information: |
Elsevier, 2019. |
| Publication Year: |
2019 |
| Collection: |
LCC:Nutrition. Foods and food supply |
| Subject Terms: |
Insulin resistance, Resveratrol, Pharmacokinetics, Tissue distribution, Excretion, Nutrition. Foods and food supply, TX341-641 |
| More Details: |
Trans-resveratrol (RES), a well-known polyphenol exerts various health-promoting benefits, including glucose homeostasis maintenance. Here, we have investigated the impact of insulin resistance (IR) on RES disposition. Rats were fed with 10%-fructose-water for 8 weeks for developing IR. The systemic exposure to RES significantly decreased (IR vs normal, AUC0-24h, 1.73, 3.79, 9.27 vs 2.50, 6.12, 12.6 μM∙h, 20, 50, 100 mg/kg, p |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
1756-4646 |
| Relation: |
http://www.sciencedirect.com/science/article/pii/S1756464619302543; https://doaj.org/toc/1756-4646 |
| DOI: |
10.1016/j.jff.2019.05.007 |
| Access URL: |
https://doaj.org/article/ff42d73fe11843a6855ca67139cb0db2 |
| Accession Number: |
edsdoj.ff42d73fe11843a6855ca67139cb0db2 |
| Database: |
Directory of Open Access Journals |
