Serum Klotho as a marker for early diagnosis of acute kidney injury after cardiac surgery
| Title: | Serum Klotho as a marker for early diagnosis of acute kidney injury after cardiac surgery |
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| Authors: | Jerin Aleš, Mosa Osama F., Kališnik Jurij M., Žibert Janez, Skitek Milan |
| Source: | Journal of Medical Biochemistry, Vol 39, Iss 2, Pp 133-139 (2020) |
| Publisher Information: | Society of Medical Biochemists of Serbia, Belgrade, 2020. |
| Publication Year: | 2020 |
| Collection: | LCC:Biochemistry |
| Subject Terms: | acute kidney injury, cardiac surgery, vreatinine, klotho protein, Biochemistry, QD415-436 |
| More Details: | Background: Early diagnosis of acute kidney injury (AKI) after cardiac surgery is based on serum creatinine which is neither a specific nor a sensitive biomarker. In our study, we investigated the role of serum Klotho in early prediction of AKI after cardiac surgery using cardiopulmonary bypass (CPB). Methods: The included patients were classified into three groups according to AKI stages using KDIGO criteria. The measurements of creatinine and Klotho levels in serum were performed before surgery, at the end of CPB, 2 hours after the end of CPB, 24 hours and 48 hours postoperatively. Results: Seventy-eight patients were included in the study. A significant increase of creatinine levels (p |
| Document Type: | article |
| File Description: | electronic resource |
| Language: | English |
| ISSN: | 1452-8258 1452-8266 |
| Relation: | https://scindeks-clanci.ceon.rs/data/pdf/1452-8258/2020/1452-82582002133J.pdf; https://doaj.org/toc/1452-8258; https://doaj.org/toc/1452-8266 |
| Access URL: | https://doaj.org/article/dfe667b34b444afab94d180dd9eccece |
| Accession Number: | edsdoj.fe667b34b444afab94d180dd9eccece |
| Database: | Directory of Open Access Journals |
| ISSN: | 14528258 14528266 |
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| Published in: | Journal of Medical Biochemistry |
| Language: | English |