Bibliographic Details
| Title: |
3-(Methoxycarbonylmethylene)isobenzofuran-1-imines as a New Class of Potential Herbicides |
| Authors: |
Fabrizio Araniti, Raffaella Mancuso, Ida Ziccarelli, Francesco Sunseri, Maria Rosa Abenavoli, Bartolo Gabriele |
| Source: |
Molecules, Vol 19, Iss 6, Pp 8261-8275 (2014) |
| Publisher Information: |
MDPI AG, 2014. |
| Publication Year: |
2014 |
| Collection: |
LCC:Organic chemistry |
| Subject Terms: |
Arabidopsis thaliana, carbonylation, isobenzofuranimines, shoot parameters, root morphology, phytotoxicity, Organic chemistry, QD241-441 |
| More Details: |
A novel class of potential herbicides, the 3-(methoxycarbonylmethylene) isobenzofuran-1-imines, has been discovered. The herbicidal activity has been tested on two particular molecules, (E)-methyl 2-[3-(butylimino)isobenzofuran-1(3H)-ylidene]acetate (1) and (E)-methyl 2-phenyl-2-[3-(phenylimino)isobenzofuran-1(3H)-ylidene]acetate (2), prepared by palladium-catalyzed oxidative carbonylation of 2-alkynylbenzamides. Both compounds 1 and 2 showed a strong phytotoxic effect on both shoot and root systems of Arabidopsis thaliana. The effects observed on the shoot were similar for both molecules, but while compound 1 showed a stronger effect on root parameters (such as primary root length, root hair and density, showing lower ED50 values), compound 2 caused important malformations in root morphology. Our results indicate that these molecules are very promising synthetic herbicides. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
1420-3049 |
| Relation: |
http://www.mdpi.com/1420-3049/19/6/8261; https://doaj.org/toc/1420-3049 |
| DOI: |
10.3390/molecules19068261 |
| Access URL: |
https://doaj.org/article/fe00e421009747648acd03a5217944de |
| Accession Number: |
edsdoj.fe00e421009747648acd03a5217944de |
| Database: |
Directory of Open Access Journals |
