Bibliographic Details
| Title: |
Integrated cross-study datasets of genetic dependencies in cancer |
| Authors: |
Clare Pacini, Joshua M. Dempster, Isabella Boyle, Emanuel Gonçalves, Hanna Najgebauer, Emre Karakoc, Dieudonne van der Meer, Andrew Barthorpe, Howard Lightfoot, Patricia Jaaks, James M. McFarland, Mathew J. Garnett, Aviad Tsherniak, Francesco Iorio |
| Source: |
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021) |
| Publisher Information: |
Nature Portfolio, 2021. |
| Publication Year: |
2021 |
| Collection: |
LCC:Science |
| Subject Terms: |
Science |
| More Details: |
The integration of independent pan-cancer CRISPR-Cas9 datasets allows better representation of genomic heterogeneity across different cancer types. Here, the authors propose a strategy for the integration of two large CRISPR-Cas9 screens and report increased coverage of molecular diversity and genetic dependencies. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2041-1723 |
| Relation: |
https://doaj.org/toc/2041-1723 |
| DOI: |
10.1038/s41467-021-21898-7 |
| Access URL: |
https://doaj.org/article/fdd2ad5966004da891cf74b4446afacf |
| Accession Number: |
edsdoj.fdd2ad5966004da891cf74b4446afacf |
| Database: |
Directory of Open Access Journals |
