Bibliographic Details
| Title: |
Brief communication: efficacy and safety of the dolutegravir/lamivudine dual therapy in antiretroviral treatment-experienced Chinese people living with HIV |
| Authors: |
Zhenyan Wang, Junyang Yang, Lin Wang, Jiangrong Wang, Yinzhong Shen, Jun Chen, Tangkai Qi, Jianjun Sun, Wei Song, Yang Tang, Shuibao Xu, Li Liu, Renfang Zhang |
| Source: |
AIDS Research and Therapy, Vol 21, Iss 1, Pp 1-5 (2024) |
| Publisher Information: |
BMC, 2024. |
| Publication Year: |
2024 |
| Collection: |
LCC:Immunologic diseases. Allergy |
| Subject Terms: |
HIV, Dolutegravir, Lamivudine, Antiretroviral, Immunologic diseases. Allergy, RC581-607 |
| More Details: |
Abstract This study aimed to evaluate the efficacy and safety of dolutegravir plus lamivudine (DTG/3TC) in antiretroviral treatment (ART)-experienced people living with HIV (PLWH). A total of 303 PLWH in Shanghai, China, who switched from triple ART to DTG/3TC between January 2019 and June 2022, with a minimum ART duration of 6 months, were retrospectively enrolled. More than 95% of PLWH maintained viral suppression with no significant changes in CD4 counts 12 months after switching. Patients transitioning from non-tenofovir (TDF)-based regimens demonstrated more pronounced improvements in lipid profiles, while those previously on TDF-based regimens showed greater enhancements in bone metabolism. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
1742-6405 |
| Relation: |
https://doaj.org/toc/1742-6405 |
| DOI: |
10.1186/s12981-024-00680-x |
| Access URL: |
https://doaj.org/article/fd4c28b7fa794a2ab3a07751ab1c31b2 |
| Accession Number: |
edsdoj.fd4c28b7fa794a2ab3a07751ab1c31b2 |
| Database: |
Directory of Open Access Journals |
|
Full text is not displayed to guests. |
Login for full access.
|
