Heart broken. An unusual case of biventricular takotsubo cardiomyopathy complicated by STEMI and Left ventricular thrombi. A case report

Bibliographic Details
Title: Heart broken. An unusual case of biventricular takotsubo cardiomyopathy complicated by STEMI and Left ventricular thrombi. A case report
Authors: Muhammad Atif Masood Noori, Hasham Saeed, Abanoub Rushdy, Sherif Elkattawy, Qirat Jawed, Nirmal Guragai, Fayez Shamoon
Source: Journal of Community Hospital Internal Medicine Perspectives, Vol 11, Iss 5, Pp 703-707 (2021)
Publisher Information: Greater Baltimore Medical Center, 2021.
Publication Year: 2021
Collection: LCC:Internal medicine
Subject Terms: takosubo cardiomyopathy, ventricular dysfunction, hemodynamic instability, lv thrombus, Internal medicine, RC31-1245
More Details: Takotsubo cardiomyopathy (TCM) is a rare occurrence in patients with troponin-positive acute coronary syndrome (ACS). It usually manifests as transient apical ballooning of the left ventricle with concomitant occurrence of right ventricular involvement in only one-third of cases. Biventricular TCM is associated with more hemodynamic instability as compared to left sided alone. Depressed ventricular systolic function and localized ventricular dyskinesis can facilitate clot formation in ventricular cavity. We present a case of 80-year-old man who presented to the ED for evaluation of hypotension. An electrocardiogram suggested acute anterior wall myocardial infarction. He underwent emergent coronary angiography and was found to have mid to apical akinesis and basal hyperkinesis with normal left coronaries and chronic total right coronary artery occlusion with excellent collaterals from left. A transthoracic echocardiography (TTE) revealed left ventricular ejection fraction 25–30% and akinesis of left and right ventricle except in the basal region. TTE with definity showed sessile thrombus. In our patient, sepsis was the most important triggering factor given initial presentation of hypotension with leukocytosis. Broad spectrum antibiotics including vancomycin and Zosyn were started considering a combination of septic and cardiogenic shock. Repeat EKG showed resolution of ST-T segment elevation but our patient remained hemodynamically unstable even with two pressure support and, ultimately, died 72 hours after admission. Herein, we emphasize on the importance right ventricular involvement and its relation to hemodynamic instability. This case highlights the importance of anticipating hemodynamic instability and clot formation in patients with biventricular Takotsubo cardiomyopathy.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2000-9666
20009666
Relation: https://doaj.org/toc/2000-9666
DOI: 10.1080/20009666.2021.1942671
Access URL: https://doaj.org/article/fd3ba8e1b1e243acbb1443528d1ded07
Accession Number: edsdoj.fd3ba8e1b1e243acbb1443528d1ded07
Database: Directory of Open Access Journals
More Details
ISSN:20009666
DOI:10.1080/20009666.2021.1942671
Published in:Journal of Community Hospital Internal Medicine Perspectives
Language:English