Bibliographic Details
Title: |
Impact of surgical and non-surgical weight loss on echocardiographic and strain parameters in Asian patients |
Authors: |
Kian Keong Poh, Vinay Bahadur Panday, Asim Shabbir, Jinghao Nicholas Ngiam, Ching-Hui Sia, Siew-Pang Chan, Sik Yin Tan, William K. F. Kong, Arthur Mark Richards, James D. Thomas |
Source: |
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024) |
Publisher Information: |
Nature Portfolio, 2024. |
Publication Year: |
2024 |
Collection: |
LCC:Medicine LCC:Science |
Subject Terms: |
Obesity, Subclinical cardiac dysfunction, Echocardiography, Speckle-tracking strain parameters, Medicine, Science |
More Details: |
Abstract Surgical weight loss (SWL) improves myocardial mechanics as measured by speckle-tracking imaging. However non-surgical versus SWL and the subsequent impact on myocardial function in overweight Asian subjects has not been evaluated. 66 patients underwent a 16-week lifestyle intervention (LSI) programme consisting of dietary interventions and exercise prescription. Echocardiography with speckle tracking was performed at baseline and post-intervention. This group was compared against a group of 12 subjects who had undergone bariatric surgery and a control group of 10 lean Asian subjects. A generalised structural equation model (gSEM) was constructed to ascertain the effect of modality of weight loss on strain parameters, adjusting for BMI. Participants attained significant weight loss after LSI (28.2 ± 2.66 kg/m2 vs. 25.8 ± 2.84 kg/m2, p = 0.001). This was associated with a non-significant trend towards improvement in strain parameters. SWL participants had significant improvement in the left ventricular global longitudinal strain (− 20.52 ± 3.34 vs. − 16.68 ± 4.15, p |
Document Type: |
article |
File Description: |
electronic resource |
Language: |
English |
ISSN: |
2045-2322 |
Relation: |
https://doaj.org/toc/2045-2322 |
DOI: |
10.1038/s41598-024-69586-y |
Access URL: |
https://doaj.org/article/fb8442c6ec674ba7a61215803672a9e1 |
Accession Number: |
edsdoj.fb8442c6ec674ba7a61215803672a9e1 |
Database: |
Directory of Open Access Journals |