| Title: |
Low-Valent Tungsten Catalyzed Carbonylative Synthesis of Benzoates from Aryl Iodides and Alcohols |
| Authors: |
Feihua Ye, Lin Lu, Zhaoyang Huang, Yunwei Huang, Lixuan Huang, Chunsheng Li, Xiang Li |
| Source: |
Molecules, Vol 29, Iss 22, p 5305 (2024) |
| Publisher Information: |
MDPI AG, 2024. |
| Publication Year: |
2024 |
| Collection: |
LCC:Organic chemistry |
| Subject Terms: |
tungsten catalyst, carbonylation, benzoates, oxidative addition, synthetic method, Organic chemistry, QD241-441 |
| More Details: |
Non-noble metals catalyzed carbonylative reactions serve as straightforward and sustainable methods for the synthesis of functionalized carbonyl-containing compounds. Herein, a low-valent-tungsten-catalyzed reaction that enables the coupling of aryl iodides and alcohols or phenols was disclosed, employing the readily available W(CO)6 as the effective catalyst and PPh3 as ligand. Under the optimal reaction conditions, aryl iodides smoothly underwent carbonylative coupling reactions with alcohols or phenols, processing the feature of broad substrate scope and good functional groups tolerance. Furthermore, this conversion can be carried out on a gram scale, showcasing significant promise in the synthesis of pharmaceutical or biologically active compounds. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
1420-3049 |
| Relation: |
https://www.mdpi.com/1420-3049/29/22/5305; https://doaj.org/toc/1420-3049 |
| DOI: |
10.3390/molecules29225305 |
| Access URL: |
https://doaj.org/article/fb745ffe0af9449088acb7252a2801dd |
| Accession Number: |
edsdoj.fb745ffe0af9449088acb7252a2801dd |
| Database: |
Directory of Open Access Journals |
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