Functional respiratory complaints among COVID-19 survivors: a prospective cohort study

Bibliographic Details
Title: Functional respiratory complaints among COVID-19 survivors: a prospective cohort study
Authors: Antoine Beurnier, Laurent Savale, Xavier Jaïs, Romain Colle, Tai Pham, Luc Morin, Sophie Bulifon, Nicolas Noël, Athénaïs Boucly, Benoit Delbarre, Nathan Ebstein, Samy Figueiredo, Matthieu Gasnier, Anatole Harrois, Etienne-Marie Jutant, Mitja Jevnikar, Sophia Keddache, Anne-Lise Lecoq, Olivier Meyrignac, Florence Parent, Jérémie Pichon, Mariana Preda, Anne Roche, Andrei Seferian, Marie-France Bellin, Thomas Gille, Emmanuelle Corruble, Olivier Sitbon, Laurent Becquemont, Xavier Monnet, Marc Humbert, David Montani, and the Comebac Investigators
Source: ERJ Open Research, Vol 9, Iss 3 (2023)
Publisher Information: European Respiratory Society, 2023.
Publication Year: 2023
Collection: LCC:Medicine
Subject Terms: Medicine
More Details: Background Dyspnoea is a common persistent symptom after COVID-19. Whether it is associated with functional respiratory disorders remains unclear. Methods We assessed the proportion and characteristics of patients with “functional respiratory complaints” (FRCs) (as defined by Nijmegen Questionnaire >22) among 177 post-COVID-19 individuals who benefited from outclinic evaluation in the COMEBAC study (i.e., symptomatic and/or intensive care unit (ICU) survivors at 4 months). In a distinct explanatory cohort of 21 consecutive individuals with unexplained post-COVID-19 dyspnoea after routine tests, we also analysed the physiological responses to incremental cardiopulmonary exercise testing (CPET). Findings In the COMEBAC cohort, 37 patients had significant FRCs (20.9%, IC95: 14.9–26.9). The prevalence of FRCs ranged from 7.2% (ICU patients) to 37.5% (non-ICU patients). The presence of FRCs was significantly associated with more severe dyspnoea, lower 6-min walk distance, more frequent psychological and neurological symptoms (cognitive complaint, anxiety, depression, insomnia and post-traumatic stress disorders) and poorer quality of life (all p
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2312-0541
23120541
Relation: http://openres.ersjournals.com/content/9/3/00063-2023.full; https://doaj.org/toc/2312-0541
DOI: 10.1183/23120541.00063-2023
Access URL: https://doaj.org/article/fa35fccc361049e196bb566de4b1f8bc
Accession Number: edsdoj.fa35fccc361049e196bb566de4b1f8bc
Database: Directory of Open Access Journals
More Details
ISSN:23120541
DOI:10.1183/23120541.00063-2023
Published in:ERJ Open Research
Language:English