The traveling heads 2.0: Multicenter reproducibility of quantitative imaging methods at 7 Tesla

Bibliographic Details
Title: The traveling heads 2.0: Multicenter reproducibility of quantitative imaging methods at 7 Tesla
Authors: Maximilian N. Voelker, Oliver Kraff, Steffen Goerke, Frederik B. Laun, Jannis Hanspach, Kerrin J. Pine, Philipp Ehses, Moritz Zaiss, Andrzej Liebert, Sina Straub, Korbinian Eckstein, Simon Robinson, Armin N. Nagel, Maria R. Stefanescu, Astrid Wollrab, Sabrina Klix, Jörg Felder, Michael Hock, Dario Bosch, Nikolaus Weiskopf, Oliver Speck, Mark E. Ladd, Harald H. Quick
Source: NeuroImage, Vol 232, Iss , Pp 117910- (2021)
Publisher Information: Elsevier, 2021.
Publication Year: 2021
Collection: LCC:Neurosciences. Biological psychiatry. Neuropsychiatry
Subject Terms: Magnetic resonance imaging, Ultrahigh field, Multicenter, Reproducibility, Quantitative imaging, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571
More Details: Object: This study evaluates inter-site and intra-site reproducibility at ten different 7 T sites for quantitative brain imaging. Material and Methods: Two subjects – termed the “traveling heads” – were imaged at ten different 7 T sites with a harmonized quantitative brain MR imaging protocol. In conjunction with the system calibration, MP2RAGE, QSM, CEST and multi-parametric mapping/relaxometry were examined. Results: Quantitative measurements with MP2RAGE showed very high reproducibility across sites and subjects, and errors were in concordance with previous results and other field strengths. QSM had high inter-site reproducibility for relevant subcortical volumes. CEST imaging revealed systematic differences between the sites, but reproducibility was comparable to results in the literature. Relaxometry had also very high agreement between sites, but due to the high sensitivity, differences caused by different applications of the B1 calibration of the two RF coil types used were observed. Conclusion: Our results show that quantitative brain imaging can be performed with high reproducibility at 7 T and with similar reliability as found at 3 T for multicenter studies of the supratentorial brain.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 1095-9572
Relation: http://www.sciencedirect.com/science/article/pii/S1053811921001877; https://doaj.org/toc/1095-9572
DOI: 10.1016/j.neuroimage.2021.117910
Access URL: https://doaj.org/article/f93edf3e26ca4e72b5d2a39970ee20ea
Accession Number: edsdoj.f93edf3e26ca4e72b5d2a39970ee20ea
Database: Directory of Open Access Journals
More Details
ISSN:10959572
DOI:10.1016/j.neuroimage.2021.117910
Published in:NeuroImage
Language:English