Overview of Corneal Transplantation for the Nonophthalmologist
| Title: | Overview of Corneal Transplantation for the Nonophthalmologist |
|---|---|
| Authors: | Yujia Zhou, MD, Theodore Wang, BS, Sonal S. Tuli, MD, Walter A. Steigleman, MD, Ankit A. Shah, MD |
| Source: | Transplantation Direct, Vol 9, Iss 2, p e1434 (2023) |
| Publisher Information: | Wolters Kluwer, 2023. |
| Publication Year: | 2023 |
| Collection: | LCC:Surgery |
| Subject Terms: | Surgery, RD1-811 |
| More Details: | Corneal transplant is a procedure that aims to replace dysfunctional corneal tissue with a transparent graft and is one of the most widely performed transplant surgeries, but its public and professional awareness is low outside of ophthalmology. Corneal tissue consists of 5 major layers that serve to maintain its structural integrity and refractive shape: the epithelium, Bowman’s layer, the stroma, Descemet’s membrane, and the endothelium. Failure or irreversible damage to any layer of the cornea may be an indication for corneal transplant, and variants of this procedure may be full thickness or selectively lamellar. Complications related to corneal transplantation may occur anywhere from during surgery to years afterward, including rejection, dehiscence, cataract, and glaucoma. Complications should be managed by an ophthalmologist, but other physicians should be aware of prophylactic medications. Topical immunosuppressants and steroids are effective for preventing and treating rejection episodes, whereas there is little evidence to support the use of systemic immunosuppression. Eye protection is recommended for any corneal transplant recipient. Physicians should counsel patients on corneal donation, especially if outside the United States, where donor tissue is in short supply. |
| Document Type: | article |
| File Description: | electronic resource |
| Language: | English |
| ISSN: | 2373-8731 00000000 |
| Relation: | http://journals.lww.com/transplantationdirect/fulltext/10.1097/TXD.0000000000001434; https://doaj.org/toc/2373-8731 |
| DOI: | 10.1097/TXD.0000000000001434 |
| Access URL: | https://doaj.org/article/f9131fa8c00542b0b0ea294142e9a848 |
| Accession Number: | edsdoj.f9131fa8c00542b0b0ea294142e9a848 |
| Database: | Directory of Open Access Journals |
| ISSN: | 23738731 00000000 |
|---|---|
| DOI: | 10.1097/TXD.0000000000001434 |
| Published in: | Transplantation Direct |
| Language: | English |