Current Diagnostic Challenges in Late-Life Depression and Neurocognitive Disorders

Bibliographic Details
Title: Current Diagnostic Challenges in Late-Life Depression and Neurocognitive Disorders
Authors: Barbara Adriani, Jan Francesco Arena, Alessandro Fioretti, Serena Mancino, Francesca Sarno, Stefano Ferracuti, Antonio Del Casale
Source: Psychiatry International, Vol 5, Iss 4, Pp 904-916 (2024)
Publisher Information: MDPI AG, 2024.
Publication Year: 2024
Collection: LCC:Psychiatry
Subject Terms: depressive disorders, mental disorders, brain disorders, vascular depression, dementia, frail elderly, Psychiatry, RC435-571
More Details: The comorbidity between late-life depression and neurocognitive disorders (NCDs) in the elderly is a subject of increasing interest within the scientific and medical community. We conducted a narrative review of clinical studies focused on depression and NCDs, primarily covering articles published over the past 25 years. Compared with younger adults, depression in the elderly is often characterized by difficulties in expressing sadness, more pronounced somatic, anxiety, and psychotic symptoms, as well as a heightened risk of suicide and cognitive impairment. Depressive symptoms in the elderly may mimic NCDs, act as prodromal signs of future NCDs, or represent a clinical dimension of dementia. NCDs and late-life depression share specific clinical similarities, particularly at illness onset, emphasizing the importance of early differential diagnosis to guide the development of precise, integrated, and tailored interventions.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2673-5318
Relation: https://www.mdpi.com/2673-5318/5/4/61; https://doaj.org/toc/2673-5318
DOI: 10.3390/psychiatryint5040061
Access URL: https://doaj.org/article/ef8f253701184e97b913377ebe363e47
Accession Number: edsdoj.f8f253701184e97b913377ebe363e47
Database: Directory of Open Access Journals
More Details
ISSN:26735318
DOI:10.3390/psychiatryint5040061
Published in:Psychiatry International
Language:English