5-Aminolevulinic Acid and Red Led in Endodontics: A Narrative Review and Case Report
| Title: | 5-Aminolevulinic Acid and Red Led in Endodontics: A Narrative Review and Case Report |
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| Authors: | Simonetta D’Ercole, Teocrito Carlesi, Tatiane Cristina Dotta, Tania Vanessa Pierfelice, Emira D’Amico, Domenico Tripodi, Giovanna Iezzi, Adriano Piattelli, Morena Petrini |
| Source: | Gels, Vol 8, Iss 11, p 697 (2022) |
| Publisher Information: | MDPI AG, 2022. |
| Publication Year: | 2022 |
| Collection: | LCC:Science LCC:Chemistry LCC:Inorganic chemistry LCC:General. Including alchemy |
| Subject Terms: | photodynamic therapy, red led, 5-aminolevulinic acid, endodontics, Science, Chemistry, QD1-999, Inorganic chemistry, QD146-197, General. Including alchemy, QD1-65 |
| More Details: | The present study aims to discuss the main factors involving the use of 5-aminolevulinic acid together with red LED light and its application in endodontic treatment through a narrative review and a case report. Persistence of microorganisms remaining on chemical-mechanical preparation or intracanal dressing is reported as the leading cause of failure in endodontics. Photodynamic therapy has become a promising antimicrobial strategy as an aid to endodontic treatment. Being easy and quick to apply, it can be used both in a single session and in several sessions, as well as not allowing forms of microbial resistance. 5-aminolevulinic acid in combination with red LED light has recently been studied in many branches of medicine, with good results against numerous types of bacteria including Enterococuss faecalis. The case report showed how bacterial count of CFU decreased by half (210 CFU/mL), after 45 min of irrigation with a gel containing 5% of 5-aminolevulinic acid compared to the sample before irrigation (420 CFU/mL). The subsequent irradiation of red LED light for 7 min, the bacterial count was equal to 0. Thus, it is concluded that the use of 5-aminolevulinic acid together with red LED light is effective in endodontic treatment. |
| Document Type: | article |
| File Description: | electronic resource |
| Language: | English |
| ISSN: | 2310-2861 |
| Relation: | https://www.mdpi.com/2310-2861/8/11/697; https://doaj.org/toc/2310-2861 |
| DOI: | 10.3390/gels8110697 |
| Access URL: | https://doaj.org/article/df86fe65731845c299ab4775f8a7b704 |
| Accession Number: | edsdoj.f86fe65731845c299ab4775f8a7b704 |
| Database: | Directory of Open Access Journals |
| ISSN: | 23102861 |
|---|---|
| DOI: | 10.3390/gels8110697 |
| Published in: | Gels |
| Language: | English |