5-aminolevulinic acid-based photodynamic therapy in combination with antifungal agents for adult kerion and facial ulcer caused by Trichophyton rubrum

Bibliographic Details
Title: 5-aminolevulinic acid-based photodynamic therapy in combination with antifungal agents for adult kerion and facial ulcer caused by Trichophyton rubrum
Authors: Juan Ji, Chu-ting Liang, Jiao-jiao Zhong, Xue Kong, Hao-xiang Xu, Chang-chun Xu, Mei-hua Fu
Source: Photodiagnosis and Photodynamic Therapy, Vol 45, Iss , Pp 103954- (2024)
Publisher Information: Elsevier, 2024.
Publication Year: 2024
Collection: LCC:Medicine (General)
Subject Terms: ALA-PDT, T.rubrum, Kerion, CARD 9 deficiency, Photodynamic Therapy, Medicine (General), R5-920
More Details: Dermatophytosis is the most common fungal infectious disease in the world, which is commonly caused by Trichophyton rubrum in China. The traditional therapies for treating dermatophytosis include topical and oral antifungal agents like terbinafine, griseofulvin, and azole antifungal drugs. However, 5-aminolevulinic acid-based photodynamic therapy (ALA-PDT) as a new alternative therapy avoids the side effects and drug resistance of traditional antifungal agents. We report two cases diagnosed as kerion and tinea faciei secondary to ulcers with CARD 9 deficiency, both of whom were infected by T.rubrum. They were both successfully treated by ALA-PDT combined with antifungal drugs, providing a feasible strategy for therapeutic choice for adult kerion and ulcer treatment.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 1572-1000
Relation: http://www.sciencedirect.com/science/article/pii/S157210002300683X; https://doaj.org/toc/1572-1000
DOI: 10.1016/j.pdpdt.2023.103954
Access URL: https://doaj.org/article/f7aec51c2c6b406aa95820775f6baac4
Accession Number: edsdoj.f7aec51c2c6b406aa95820775f6baac4
Database: Directory of Open Access Journals
More Details
ISSN:15721000
DOI:10.1016/j.pdpdt.2023.103954
Published in:Photodiagnosis and Photodynamic Therapy
Language:English