Interventions Designed to Improve Adherence to Growth Hormone Treatment for Pediatric Patients and Their Families: A Narrative Review

Bibliographic Details
Title: Interventions Designed to Improve Adherence to Growth Hormone Treatment for Pediatric Patients and Their Families: A Narrative Review
Authors: Selina Graham, Sophia Quirke-McFarlane, Vivian Auyeung, John Weinman
Source: Pharmaceutics, Vol 14, Iss 11, p 2373 (2022)
Publisher Information: MDPI AG, 2022.
Publication Year: 2022
Collection: LCC:Pharmacy and materia medica
Subject Terms: children, pediatric, injection device, patient choice, short stature, Pharmacy and materia medica, RS1-441
More Details: Even though growth hormone (GH) treatment is still the only active treatment option to correct growth failure and increase stature for patients with GH deficiencies, evidence has shown that non-adherence remains high. The aim of this review was to identify and review the existing interventional strategies that have been designed to address and improve adherence to GH treatment for pediatric patients and their families. An extensive search of several electronic databases was undertaken to identify relevant interventional studies, published in English, between 1985 and 2021. Additional search strategies included hand-searching topic review articles to identify eligible studies. Articles were screened against the inclusion eligibility criteria and data on sample characteristics, intervention features, and key findings was extracted. A total of fifteen interventional studies were included in the review. The interventions identified were divided into two broad categories: novel injection devices, and patient choice of device. In conclusions, this review acknowledges that there is a lack of evidence-based, theory-driven intervention strategies, designed with the purpose of optimizing treatment adherence and improve clinical and psychosocial outcomes.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 1999-4923
Relation: https://www.mdpi.com/1999-4923/14/11/2373; https://doaj.org/toc/1999-4923
DOI: 10.3390/pharmaceutics14112373
Access URL: https://doaj.org/article/f6aa97b16771497babd849bf79598081
Accession Number: edsdoj.f6aa97b16771497babd849bf79598081
Database: Directory of Open Access Journals
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More Details
ISSN:19994923
DOI:10.3390/pharmaceutics14112373
Published in:Pharmaceutics
Language:English