Intracranial stenting with the Neuroform Atlas Stent for symptomatic intracranial atherosclerotic stenosis: a bi-center retrospective analysis including stroke recurrence nomogram

Bibliographic Details
Title: Intracranial stenting with the Neuroform Atlas Stent for symptomatic intracranial atherosclerotic stenosis: a bi-center retrospective analysis including stroke recurrence nomogram
Authors: Weicheng Peng, Haiyang Ma, Xinli Xiang, Rui Zhao, Meng Lv, Sheng Xu, Yuhua Jiang, Zhiqiang Hu, Feng Guan
Source: Frontiers in Neurology, Vol 16 (2025)
Publisher Information: Frontiers Media S.A., 2025.
Publication Year: 2025
Collection: LCC:Neurology. Diseases of the nervous system
Subject Terms: intracranial atherosclerotic stenosis, ischemic stroke, intracranial stenting, Neuroform Atlas Stent, predictive nomogram, Neurology. Diseases of the nervous system, RC346-429
More Details: BackgroundIntracranial stenting with the Neuroform Atlas Stent is an emerging option for patients with symptomatic intracranial atherosclerotic stenosis (sICAS) who do not respond to intensive medical treatment. However, the efficacy, safety, and risk factors associated with postoperative stroke recurrence remain controversial.MethodsA total of 326 consecutive patients with sICAS treated with intracranial stenting using the Neuroform Atlas Stent were retrospectively analyzed to evaluate the efficacy and safety of the procedure. Patients were randomly assigned to a training set and a validation set in a 7:3 ratio. Significant variables in the univariate logistic analyses were included in the final multivariate logistic regression analyses in the training set. Subsequently, we developed a predictive nomogram for sICAS treated with a Neuroform Atlas Stent to predict the likelihood of stroke recurrence at 6 months.ResultsThe overall mean stenosis rate of the target artery was 88.85% ± 6.53% before the stenting (T0), 47.58% ± 9.94% at the end of the procedure (T1), and 40.21% ± 7.77% at the 6-month follow-up (T2). The stenosis rate was statistically significant between T0 and T1 (p
Document Type: article
File Description: electronic resource
Language: English
ISSN: 1664-2295
Relation: https://www.frontiersin.org/articles/10.3389/fneur.2025.1507339/full; https://doaj.org/toc/1664-2295
DOI: 10.3389/fneur.2025.1507339
Access URL: https://doaj.org/article/df5ea1be5463448cb78b9c9cd50cc2b5
Accession Number: edsdoj.f5ea1be5463448cb78b9c9cd50cc2b5
Database: Directory of Open Access Journals
More Details
ISSN:16642295
DOI:10.3389/fneur.2025.1507339
Published in:Frontiers in Neurology
Language:English