Clinical Outcomes and Adverse Events of Endoscopic Submucosal Dissection for Gastric Tube Cancer after Esophagectomy

Bibliographic Details
Title: Clinical Outcomes and Adverse Events of Endoscopic Submucosal Dissection for Gastric Tube Cancer after Esophagectomy
Authors: Ko Watanabe, Takuto Hikichi, Jun Nakamura, Minami Hashimoto, Tadayuki Takagi, Rei Suzuki, Mitsuru Sugimoto, Hitomi Kikuchi, Naoki Konno, Mika Takasumi, Yuki Sato, Hiroki Irie, Katsutoshi Obara, Hiromasa Ohira
Source: Gastroenterology Research and Practice, Vol 2019 (2019)
Publisher Information: Hindawi Limited, 2019.
Publication Year: 2019
Collection: LCC:Diseases of the digestive system. Gastroenterology
Subject Terms: Diseases of the digestive system. Gastroenterology, RC799-869
More Details: Background and Aim. The clinical outcomes of endoscopic submucosal dissection (ESD) for gastric tube cancer (GTC) after esophagectomy remain unclear. The aim of this study was to evaluate the clinical outcomes and safety of ESD for GTC. Patients and Methods. Twenty GTC lesions in 18 consecutive patients who underwent ESD between February 2008 and June 2018 were included in this retrospective study. The endpoints were the treatment outcomes of ESD (i.e., en bloc resection rate, complete en bloc resection rate, and curative resection rate), the adverse events following ESD, and the long-term outcomes. Results. The en bloc resection rate was 100%, while the complete en bloc resection rate and curative resection rate were 80% each. Adverse events were observed in 16.7% (3/18) of patients: one postoperative bleeding, 1 intraoperative perforation that required emergency surgery, and 1 pyothorax that required chest drainage. The 1-, 3-, and 5-year overall survival rates were 100%, 70.9%, and 70.9%, respectively. Although local recurrence was detected in 1 case of noncurative resection, no GTC- or ESD-related deaths were observed. Conclusion. ESD for GTC was feasible and acceptable to enable en bloc resection and to prevent cancer death. However, ESD for GTC should be performed more carefully than common gastric ESD because serious adverse events specific to the gastric tube may occur.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 1687-6121
1687-630X
Relation: https://doaj.org/toc/1687-6121; https://doaj.org/toc/1687-630X
DOI: 10.1155/2019/2836860
Access URL: https://doaj.org/article/af5ce4a7c1224a9ca7ab0e0227b29773
Accession Number: edsdoj.f5ce4a7c1224a9ca7ab0e0227b29773
Database: Directory of Open Access Journals
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More Details
ISSN:16876121
1687630X
DOI:10.1155/2019/2836860
Published in:Gastroenterology Research and Practice
Language:English