Academic Journal
Clinical Outcomes and Adverse Events of Endoscopic Submucosal Dissection for Gastric Tube Cancer after Esophagectomy
Title: | Clinical Outcomes and Adverse Events of Endoscopic Submucosal Dissection for Gastric Tube Cancer after Esophagectomy |
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Authors: | Ko Watanabe, Takuto Hikichi, Jun Nakamura, Minami Hashimoto, Tadayuki Takagi, Rei Suzuki, Mitsuru Sugimoto, Hitomi Kikuchi, Naoki Konno, Mika Takasumi, Yuki Sato, Hiroki Irie, Katsutoshi Obara, Hiromasa Ohira |
Source: | Gastroenterology Research and Practice, Vol 2019 (2019) |
Publisher Information: | Hindawi Limited, 2019. |
Publication Year: | 2019 |
Collection: | LCC:Diseases of the digestive system. Gastroenterology |
Subject Terms: | Diseases of the digestive system. Gastroenterology, RC799-869 |
More Details: | Background and Aim. The clinical outcomes of endoscopic submucosal dissection (ESD) for gastric tube cancer (GTC) after esophagectomy remain unclear. The aim of this study was to evaluate the clinical outcomes and safety of ESD for GTC. Patients and Methods. Twenty GTC lesions in 18 consecutive patients who underwent ESD between February 2008 and June 2018 were included in this retrospective study. The endpoints were the treatment outcomes of ESD (i.e., en bloc resection rate, complete en bloc resection rate, and curative resection rate), the adverse events following ESD, and the long-term outcomes. Results. The en bloc resection rate was 100%, while the complete en bloc resection rate and curative resection rate were 80% each. Adverse events were observed in 16.7% (3/18) of patients: one postoperative bleeding, 1 intraoperative perforation that required emergency surgery, and 1 pyothorax that required chest drainage. The 1-, 3-, and 5-year overall survival rates were 100%, 70.9%, and 70.9%, respectively. Although local recurrence was detected in 1 case of noncurative resection, no GTC- or ESD-related deaths were observed. Conclusion. ESD for GTC was feasible and acceptable to enable en bloc resection and to prevent cancer death. However, ESD for GTC should be performed more carefully than common gastric ESD because serious adverse events specific to the gastric tube may occur. |
Document Type: | article |
File Description: | electronic resource |
Language: | English |
ISSN: | 1687-6121 1687-630X |
Relation: | https://doaj.org/toc/1687-6121; https://doaj.org/toc/1687-630X |
DOI: | 10.1155/2019/2836860 |
Access URL: | https://doaj.org/article/af5ce4a7c1224a9ca7ab0e0227b29773 |
Accession Number: | edsdoj.f5ce4a7c1224a9ca7ab0e0227b29773 |
Database: | Directory of Open Access Journals |
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ISSN: | 16876121 1687630X |
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DOI: | 10.1155/2019/2836860 |
Published in: | Gastroenterology Research and Practice |
Language: | English |