Bibliographic Details
| Title: |
Austin-Type Meroterpenoids from Fungi Reported in the Last Five Decades: A Review |
| Authors: |
Jia-Li He, Chang-Jing Chen, Yong-Hong Liu, Cheng-Hai Gao, Rui-Ping Wang, Wen-Fei Zhang, Meng Bai |
| Source: |
Journal of Fungi, Vol 10, Iss 2, p 162 (2024) |
| Publisher Information: |
MDPI AG, 2024. |
| Publication Year: |
2024 |
| Collection: |
LCC:Biology (General) |
| Subject Terms: |
fungi, austin-type meroterpenoids, structural diversity, biological activity, Biology (General), QH301-705.5 |
| More Details: |
Austin was first isolated as a novel polyisoprenoid mycotoxin from Aspergillus ustus in 1976. Subsequently, some new austin-type meroterpenoids (ATMTs) have been continually found. This review attempts to give a comprehensive summary of progress on the isolation, chemical structural features, biological activities, and fungal biodiversity of 104 novel ATMTs from 5 genera of terrestrial- and marine-derived fungi reported from October 1976 to January 2023. The genera of Penicillium and Aspergillus are the two dominant producers, producing 63.5% and 30.8% of ATMTs, respectively. Moreover, about 26.9% of ATMTs display various pronounced bioactivities, including insecticidal, anti-inflammatory, cytotoxicity, antibacterial, and PTP1B inhibitory activities. The chemical diversity and potential activities of these novel fungal ATMTs are reviewed for a better understanding, and a relevant summary focusing on the source fungi and their taxonomy is provided to shed light on the future development and research of austin-type meroterpenoids. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2309-608X |
| Relation: |
https://www.mdpi.com/2309-608X/10/2/162; https://doaj.org/toc/2309-608X |
| DOI: |
10.3390/jof10020162 |
| Access URL: |
https://doaj.org/article/f556e6d55c5b456290e9cb5829e48c3a |
| Accession Number: |
edsdoj.f556e6d55c5b456290e9cb5829e48c3a |
| Database: |
Directory of Open Access Journals |
