Importance of Nectin2, NUF2, and Nectin4 Gene Expression in the Pathogenesis of Different Subtypes of Breast Cancer
Title: | Importance of Nectin2, NUF2, and Nectin4 Gene Expression in the Pathogenesis of Different Subtypes of Breast Cancer |
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Authors: | Zahra Roshanizadeh, Mohammad Reza Haghshenas, Amin Ramezani, Neda Shajari, Sedigheh Tahmasebi, Majid Akrami, Abbas Ghaderi |
Source: | Middle East Journal of Cancer, Vol 15, Iss 4, Pp 281-288 (2024) |
Publisher Information: | Shiraz University of Medical Sciences, 2024. |
Publication Year: | 2024 |
Collection: | LCC:Neoplasms. Tumors. Oncology. Including cancer and carcinogens |
Subject Terms: | triple negative breast neoplasms, biomarker, estrogen receptor, progesterone receptor, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282 |
More Details: | Background: The targeted therapy using breast cancer (BC)-associated biomarkers has significantly minimized the side-effects of BC treatment. This study aims to elucidate the role of Nectin2, NUF2, and Nectin4 gene expression in the pathogenesis of BC.Method: In this case-control study, the expression of Nectin2, Nectin4, and NUF2 genes was investigated through real-time polymerase chain reaction assay in 46 tumor tissues from BC patients and 46 adjacent non-tumorous tissues as a control group. Data were analyzed using SPSS-21 software, employing independent t-tests and one-way ANOVA. A P-value of |
Document Type: | article |
File Description: | electronic resource |
Language: | English |
ISSN: | 2008-6709 2008-6687 |
Relation: | https://mejc.sums.ac.ir/article_49992_570871993d327640c725391ced27fb80.pdf; https://doaj.org/toc/2008-6709; https://doaj.org/toc/2008-6687 |
DOI: | 10.30476/mejc.2024.100701.1997 |
Access URL: | https://doaj.org/article/f526d90ed14545fb9f9fcbd448ba4918 |
Accession Number: | edsdoj.f526d90ed14545fb9f9fcbd448ba4918 |
Database: | Directory of Open Access Journals |
ISSN: | 20086709 20086687 |
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DOI: | 10.30476/mejc.2024.100701.1997 |
Published in: | Middle East Journal of Cancer |
Language: | English |