Importance of Nectin2, NUF2, and Nectin4 Gene Expression in the Pathogenesis of Different Subtypes of Breast Cancer

Bibliographic Details
Title: Importance of Nectin2, NUF2, and Nectin4 Gene Expression in the Pathogenesis of Different Subtypes of Breast Cancer
Authors: Zahra Roshanizadeh, Mohammad Reza Haghshenas, Amin Ramezani, Neda Shajari, Sedigheh Tahmasebi, Majid Akrami, Abbas Ghaderi
Source: Middle East Journal of Cancer, Vol 15, Iss 4, Pp 281-288 (2024)
Publisher Information: Shiraz University of Medical Sciences, 2024.
Publication Year: 2024
Collection: LCC:Neoplasms. Tumors. Oncology. Including cancer and carcinogens
Subject Terms: triple negative breast neoplasms, biomarker, estrogen receptor, progesterone receptor, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
More Details: Background: The targeted therapy using breast cancer (BC)-associated biomarkers has significantly minimized the side-effects of BC treatment. This study aims to elucidate the role of Nectin2, NUF2, and Nectin4 gene expression in the pathogenesis of BC.Method: In this case-control study, the expression of Nectin2, Nectin4, and NUF2 genes was investigated through real-time polymerase chain reaction assay in 46 tumor tissues from BC patients and 46 adjacent non-tumorous tissues as a control group. Data were analyzed using SPSS-21 software, employing independent t-tests and one-way ANOVA. A P-value of
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2008-6709
2008-6687
Relation: https://mejc.sums.ac.ir/article_49992_570871993d327640c725391ced27fb80.pdf; https://doaj.org/toc/2008-6709; https://doaj.org/toc/2008-6687
DOI: 10.30476/mejc.2024.100701.1997
Access URL: https://doaj.org/article/f526d90ed14545fb9f9fcbd448ba4918
Accession Number: edsdoj.f526d90ed14545fb9f9fcbd448ba4918
Database: Directory of Open Access Journals
More Details
ISSN:20086709
20086687
DOI:10.30476/mejc.2024.100701.1997
Published in:Middle East Journal of Cancer
Language:English