Non-Occlusive Mesenteric Ischemia in Children With Diabetic Ketoacidosis: Case Report and Review of Literature

Bibliographic Details
Title: Non-Occlusive Mesenteric Ischemia in Children With Diabetic Ketoacidosis: Case Report and Review of Literature
Authors: Giulio Frontino, Raffaella Di Tonno, Valeria Castorani, Andrea Rigamonti, Elisa Morotti, Federica Sandullo, Francesco Scialabba, Francesca Arrigoni, Riccardo Foglino, Benedetta Dionisi, Chiara Irene Carla Ferri, Salvatore Zirpoli, Graziano Barera, Franco Meschi, Riccardo Bonfanti
Source: Frontiers in Endocrinology, Vol 13 (2022)
Publisher Information: Frontiers Media S.A., 2022.
Publication Year: 2022
Collection: LCC:Diseases of the endocrine glands. Clinical endocrinology
Subject Terms: non-occlusive mesenteric ischemia (NOMI), DKA (diabetic ketoacidosis), insulin pump (CSII: continuous subcutaneous insulin infusion), acute kidney injury, hyperosmolar (hyperglycemic) coma, T1DM (type 1 diabetes mellitus), Diseases of the endocrine glands. Clinical endocrinology, RC648-665
More Details: IntroductionDespite the use of technology, recurrent diabetic ketoacidosis (DKA) prevention remains an unmet need in children and adolescents with T1D and may be accompanied by life-threatening acute complications. We present a rare case of non-occlusive mesenteric ischemia (NOMI) with overt manifestation after DKA resolution and a discussion of recent literature addressing DKA-associated NOMI epidemiology and pathogenesis in children and adolescents.Case PresentationA 13-year-old female with previously diagnosed T1D, was admitted at our emergency department with hypovolemic shock, DKA, hyperosmolar state and acute kidney injury (AKI). Mildly progressive abdominal pain persisted after DKA correction and after repeated ultrasound evaluations ultimately suspect for intestinal perforation, an intraoperative diagnosis of NOMI was made.ConclusionThe diagnosis of DKA-associated NOMI must be suspected in pediatric patients with DKA, persistent abdominal pain, and severe dehydration even after DKA resolution.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 1664-2392
Relation: https://www.frontiersin.org/articles/10.3389/fendo.2022.900325/full; https://doaj.org/toc/1664-2392
DOI: 10.3389/fendo.2022.900325
Access URL: https://doaj.org/article/f4d5bd07237a482c975236f4b4486af3
Accession Number: edsdoj.f4d5bd07237a482c975236f4b4486af3
Database: Directory of Open Access Journals
More Details
ISSN:16642392
DOI:10.3389/fendo.2022.900325
Published in:Frontiers in Endocrinology
Language:English