Academic Journal
A Case with Hepatic Involvement Mimicking Metastatic Disease in Multiple Myeloma
| Title: | A Case with Hepatic Involvement Mimicking Metastatic Disease in Multiple Myeloma |
|---|---|
| Authors: | Mert Erciyestepe, Tarık Onur Tiryaki, İpek Yönal Hindilerden, Gülçin Yeğen, Meliha Nalçacı |
| Source: | Case Reports in Hematology, Vol 2020 (2020) |
| Publisher Information: | Wiley, 2020. |
| Publication Year: | 2020 |
| Collection: | LCC:Diseases of the blood and blood-forming organs |
| Subject Terms: | Diseases of the blood and blood-forming organs, RC633-647.5 |
| More Details: | Multiple myeloma is a type of plasma cell disorder and can be seen in different forms. According to current knowledge, it is not a curable disease. Smoldering multiple myeloma (SMM) is an asymptomatic clonal plasma cell disorder and distinguished from monoclonal gammopathy of undetermined significance by a much higher risk of progression to multiple myeloma. We present a 53-year-old female patient who started with SMM which turned into multiple myeloma after four years. Despite 26 cycles of lenalidomide treatment, we performed the second autologous stem transplantation. After 12 years from the diagnosis of the disease, it was transformed into plasma cell leukemia and widespread nodular lesions were seen in the liver. Different presentations could be seen due to malignant plasma cell infiltrations or primary amyloidosis. Liver involvement is one of them and is less common than other organ involvement. We report a case of myeloma presenting with extensive nodular involvement in the liver and misdiagnosed as metastatic disease. It is important because of its rarity and change of the treatment approach. |
| Document Type: | article |
| File Description: | electronic resource |
| Language: | English |
| ISSN: | 2090-6560 2090-6579 |
| Relation: | https://doaj.org/toc/2090-6560; https://doaj.org/toc/2090-6579 |
| DOI: | 10.1155/2020/5738319 |
| Access URL: | https://doaj.org/article/f3e67846fe4d4eaa89d51ec64492105a |
| Accession Number: | edsdoj.f3e67846fe4d4eaa89d51ec64492105a |
| Database: | Directory of Open Access Journals |
| Full text is not displayed to guests. | Login for full access. |
| ISSN: | 20906560 20906579 |
|---|---|
| DOI: | 10.1155/2020/5738319 |
| Published in: | Case Reports in Hematology |
| Language: | English |