Bibliographic Details
| Title: |
Dare to Compare. Development of Atherosclerotic Lesions in Human, Mouse, and Zebrafish |
| Authors: |
Viviana L. Vedder, Zouhair Aherrahrou, Jeanette Erdmann |
| Source: |
Frontiers in Cardiovascular Medicine, Vol 7 (2020) |
| Publisher Information: |
Frontiers Media S.A., 2020. |
| Publication Year: |
2020 |
| Collection: |
LCC:Diseases of the circulatory (Cardiovascular) system |
| Subject Terms: |
atherosclerosis, animal models, mouse, zebrafish, immune response, human disease, Diseases of the circulatory (Cardiovascular) system, RC666-701 |
| More Details: |
Cardiovascular diseases, such as atherosclerosis, are the leading cause of death worldwide. Although mice are currently the most commonly used model for atherosclerosis, zebrafish are emerging as an alternative, especially for inflammatory and lipid metabolism studies. Here, we review the history of in vivo atherosclerosis models and highlight the potential for future studies on inflammatory responses in lipid deposits in zebrafish, based on known immune reactions in humans and mice, in anticipation of new zebrafish models with more advanced atherosclerotic plaques. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2297-055X |
| Relation: |
https://www.frontiersin.org/article/10.3389/fcvm.2020.00109/full; https://doaj.org/toc/2297-055X |
| DOI: |
10.3389/fcvm.2020.00109 |
| Access URL: |
https://doaj.org/article/f3ac9eb3866d49fc8039c4631691ec1b |
| Accession Number: |
edsdoj.f3ac9eb3866d49fc8039c4631691ec1b |
| Database: |
Directory of Open Access Journals |
