Bibliographic Details
| Title: |
Stereoselective OsO4-mediated dihydroxylation of β-substituted α-trialkylsilyl-β,γ-unsaturated esters |
| Authors: |
Anna C. Seal, Michael P. Jennings |
| Source: |
Results in Chemistry, Vol 3, Iss , Pp 100250- (2021) |
| Publisher Information: |
Elsevier, 2021. |
| Publication Year: |
2021 |
| Collection: |
LCC:Chemistry |
| Subject Terms: |
Allylsilane, Dihydroxylation, Natural products, Olefination, Diastereoselective synthesis, Chemistry, QD1-999 |
| More Details: |
The dihydroxylation of various of α-trialkylsilyl-β,γ-unsaturated esters with OsO4 and NMO has been explored. It has been revealed that these reactions readily allow for a stereoselective dihydroxylation with high levels of dr (>20/1) to afford anti-aldol products with three contiguous stereogenic centers in modest overall yields. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2211-7156 |
| Relation: |
http://www.sciencedirect.com/science/article/pii/S2211715621001557; https://doaj.org/toc/2211-7156 |
| DOI: |
10.1016/j.rechem.2021.100250 |
| Access URL: |
https://doaj.org/article/f35a48c8c5e8410a87c28e5865ff6a7f |
| Accession Number: |
edsdoj.f35a48c8c5e8410a87c28e5865ff6a7f |
| Database: |
Directory of Open Access Journals |
