Bibliographic Details
| Title: |
A comparative study of efficacy and safety of alcaftadine 0.25% versus olopatadine hydrochloride 0.2% in allergic conjunctivitis at a tertiary care hospital |
| Authors: |
Akila Krishnan, C R Jayanthi, Sriya Sridhar |
| Source: |
Kerala Journal of Ophthalmology, Vol 34, Iss 3, Pp 227-233 (2022) |
| Publisher Information: |
Wolters Kluwer Medknow Publications, 2022. |
| Publication Year: |
2022 |
| Collection: |
LCC:Ophthalmology |
| Subject Terms: |
alcaftadine 0.25% eye drops, allergic conjunctivitis, conjunctival hyperemia scale, olopatadine hydrochloride 0.2% eye drops, total ocular symptoms score, Ophthalmology, RE1-994 |
| More Details: |
Background: Ocular itching is the hallmark symptom of allergic conjunctivitis, accompanied by tearing, conjunctival redness, eyelid swelling, and chemosis. Alcaftadine and olopatadine hydrochloride are classified as dual-acting antiallergic agents, used in the treatment of allergic conjunctivitis. Objective: The aim is to compare the efficacy and safety of alcaftadine 0.25% and olopatadine hydrochloride 0.2% eye drops among patients with allergic conjunctivitis. Settings and Design: Ophthalmology outpatient department at Minto Ophthalmic Hospital, Bangalore Medical College and Research Institute, Bengaluru; prospective, randomized, comparative study. Subjects and Methods: This study was conducted among 120 patients suffering from grade 3 Allergic conjunctivitis and efficacy measured in terms of proportion of patients achieving symptomatic relief of allergic ocular signs and symptoms from grade 3 to grade 0 from baseline to 2 weeks, using Total Ocular Symptoms Score (TOSS) and Conjunctival Hyperemia scale. Safety assessed by monitoring treatment-emergent adverse effects. Continuous data assessed by unpaired, paired t-test and repeated measures-ANOVA and categorical data by Chi-square test. P |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
0976-6677 |
| Relation: |
http://www.kjophthal.com/article.asp?issn=0976-6677;year=2022;volume=34;issue=3;spage=227;epage=233;aulast=Krishnan; https://doaj.org/toc/0976-6677 |
| DOI: |
10.4103/kjo.kjo_185_21 |
| Access URL: |
https://doaj.org/article/cf352bde012f41999ecf3ecd374bfb5b |
| Accession Number: |
edsdoj.f352bde012f41999ecf3ecd374bfb5b |
| Database: |
Directory of Open Access Journals |
