Verification of the performance of the Bispectral Index as a hypnotic depth indicator during dexmedetomidine sedation
| Title: | Verification of the performance of the Bispectral Index as a hypnotic depth indicator during dexmedetomidine sedation |
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| Authors: | Seunghee Ki, Dongeon Lee, Wonjin Lee, Kwangrae Cho, Yongjae Han, Jeonghan Lee |
| Source: | Anesthesia and Pain Medicine, Vol 17, Iss 1, Pp 44-51 (2022) |
| Publisher Information: | Korean Society of Anesthesiologists, 2022. |
| Publication Year: | 2022 |
| Collection: | LCC:Anesthesiology LCC:Medicine |
| Subject Terms: | anesthesia, spinal, consciousness monitors, dexmedetomidine, hypnotics and sedatives, Anesthesiology, RD78.3-87.3, Medicine |
| More Details: | Background Differences in the effects of propofol and dexmedetomidine sedation on electroencephalogram patterns have been reported previously. However, the reliability of the Bispectral Index (BIS) value for assessing the sedation caused by dexmedetomidine remains debatable. The purpose of this study is to evaluate the correlation between the BIS value and the Modified Observer’s Assessment of Alertness/Sedation (MOAA/S) scale in patients sedated with dexmedetomidine. Methods Forty-two patients aged 20–80 years, who were scheduled for surgery under spinal anesthesia were enrolled. Spinal anesthesia was performed using 0.5% bupivacaine, which was followed by dexmedetomidine infusion (loading dose, 0.5–1 μg/kg for 10 min; maintenance dose, 0.3–0.6 μg/kg/h). The MOAA/S score was used to evaluate the level of sedation. Results A total of 215082 MOAA/S scores and BIS data pairs were analyzed. The baseline variability of the BIS value was 7.024%, and BIS value decreased, as the MOAA/S scored decreased. The correlation coefficient and prediction probability between the two measurements were 0.566 (P < 0.0001) and 0.636, respectively. The mean ± standard deviation values of the BIS were 87.22 ± 7.06, 75.85 ± 9.81, and 68.29 ± 12.65 when the MOAA/S scores were 5, 3, and 1, respectively. Furthermore, the cut-off BIS values in the receiver operating characteristic analysis at MOAA/S scores of 5, 3, and 1 were 82, 79, and 73, respectively. Conclusions The BIS values were significantly correlated with the MOAA/S scores. Thus, the BIS along with the clinical sedation scale might prove useful in assessing the hypnotic depth of a patient during sedation with dexmedetomidine. |
| Document Type: | article |
| File Description: | electronic resource |
| Language: | English |
| ISSN: | 1975-5171 2383-7977 |
| Relation: | http://www.anesth-pain-med.org/upload/pdf/apm-21065.pdf; https://doaj.org/toc/1975-5171; https://doaj.org/toc/2383-7977 |
| DOI: | 10.17085/apm.21065 |
| Access URL: | https://doaj.org/article/f2a83693732b495186027af76923e06f |
| Accession Number: | edsdoj.f2a83693732b495186027af76923e06f |
| Database: | Directory of Open Access Journals |
| ISSN: | 19755171 23837977 |
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| DOI: | 10.17085/apm.21065 |
| Published in: | Anesthesia and Pain Medicine |
| Language: | English |