Restless Legs Syndrome: From Diagnosis to Treatment

Bibliographic Details
Title: Restless Legs Syndrome: From Diagnosis to Treatment
Authors: Yıldız Değirmenci, Rashad İsmayılov
Source: Düzce Tıp Fakültesi Dergisi, Vol 25, Iss 3, Pp 212-217 (2023)
Publisher Information: Duzce University, 2023.
Publication Year: 2023
Collection: LCC:Medicine
LCC:Medicine (General)
Subject Terms: restless legs syndrome, augmentation, iron deficiency, iron therapy, huzursuz bacaklar sendromu, augmentasyon, demir eksikliği, demir tedavisi, Medicine, Medicine (General), R5-920
More Details: Restless legs syndrome (RLS) can be described by an urge to move limbs that typically coincides with an uncomfortable sensation. When at rest or inactivity, signs may start or develop worse; they usually go away when one moves or gets up for a walk. RLS can be both idiopathic or secondary to many kinds of health conditions, such as deficiency of iron, diabetes, obesity, hypothyroidism, and chronic renal failure. At the admission, secondary causes and iron tests, such as transferrin saturation and ferritin, must be evaluated. Assessments should be repeated when symptoms worsen, or when augmentation develops. Augmentation is a significant adverse effect of therapy by levodopa and dopamine agonists. More severe signs, early appearance of symptoms, and spreading of symptoms from the legs to other body parts are indicative of augmentation. Non-pharmacological treatments help some RLS patients control their symptoms. Iron-replacement therapy is a first-line treatment option for patients with indications of low body iron stores. The use of α2δ ligands as initial treatments instead of dopamine agonists has been recommended recently.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 1307-671X
Relation: https://dergipark.org.tr/en/download/article-file/3540170; https://doaj.org/toc/1307-671X
DOI: 10.18678/dtfd.1391450
Access URL: https://doaj.org/article/f1db0ed278324b3689a3517d7eb33b15
Accession Number: edsdoj.f1db0ed278324b3689a3517d7eb33b15
Database: Directory of Open Access Journals
More Details
ISSN:1307671X
DOI:10.18678/dtfd.1391450
Published in:Düzce Tıp Fakültesi Dergisi
Language:English