Is There a Correlation Between Pulmonary Inflammation Index With COVID-19 Disease Severity and Outcome?
| Title: | Is There a Correlation Between Pulmonary Inflammation Index With COVID-19 Disease Severity and Outcome? |
|---|---|
| Authors: | Islam Galal, Aliae AR Mohamed Hussein, Mohammed M. Mohammed, Howaida K. Abd ElAal, Karim Aly, Islam ElNakeeb, Ahmed Hamdy Ahmed Mhsb, Mohamed M. Amin |
| Source: | SVU - International Journal of Medical Sciences, Vol 5, Iss 2, Pp 35-50 (2022) |
| Publisher Information: | South Valley University, Faculty of Medicine, 2022. |
| Publication Year: | 2022 |
| Collection: | LCC:Medicine |
| Subject Terms: | covid-19, coronavirus disease, sars-cov-2, chest hrct, pulmonary inflammation index, ferritin, crp, severity, icu, outcomes, Medicine |
| More Details: | Background: The radiologic pulmonary inflammatory index (PII) may be used as an early predictor of inflammation as laboratory assessments in COVID-19 cases. The purpose of this study was tocompare the clinical and radiological features between cases of COVID-19 necessitating admittance to the intensive care unit (ICU) and those who did not, and to correlate the PII with other inflammatory markers and outcomes. Patients and methods: 72 patients consecutively admitted with confirmed COVID-19. Their electronic records were retrospectively revised and the demographic, clinical, laboratory (complete blood count, C- reactive protein, D dimer, and serum ferritin), High resolution computed tomography (HRCT) data, PII, and the outcomes of the patients were analyzed. Results: They were 50/50%, males/females, with mean age 47.1 ± 16.8 years. During their stay, 15.3% necessitated ICU admittance, 68% cured and discharged, 9 cases referred and 6.9% died. The baseline lesions identified were ground-glass opacification recognized in (93%), higher PII and >3 lobes affection was considerably recorded in those who required ICU admittance (P= 0.041 and 0.013). There was a mild positive correlation between PII with age (r=0.264, P=0.031) and other prognostic inflammatory indicators as ferritin (r=0.225, P=0.048), D Dimer (r=0.271, P=0.043), and serum creatinine. Conclusions: The use of PII together with clinical and laboratory data may be valuable in defining the inflammatory state of COVID-19. This may allow clinicians to avoid the progression of the illness and improve the cure rates by proper early intervention. |
| Document Type: | article |
| File Description: | electronic resource |
| Language: | English |
| ISSN: | 2735-427X 2636-3402 |
| Relation: | https://svuijm.journals.ekb.eg/article_222349.html; https://doaj.org/toc/2735-427X; https://doaj.org/toc/2636-3402 |
| DOI: | 10.21608/svuijm.2022.119822.1271 |
| Access URL: | https://doaj.org/article/cdf1db00f9b948ddb14a28674bd31870 |
| Accession Number: | edsdoj.f1db00f9b948ddb14a28674bd31870 |
| Database: | Directory of Open Access Journals |
| ISSN: | 2735427X 26363402 |
|---|---|
| DOI: | 10.21608/svuijm.2022.119822.1271 |
| Published in: | SVU - International Journal of Medical Sciences |
| Language: | English |